Evidence map›Paper›PMID 39076697›Full record

ArticleReviews in cardiovascular medicine2023

LDL-C: An Important Independent Risk Factor for New-Onset Heart Block in Patients with Severe Aortic Stenosis and Heart Failure after TAVR.

Mei Dong, Lizhen Wang, Gary Tse, Tao Dai, Tonglian Lv, Nan Zhang, Lihong Wang, Zhicheng Xiao, Tienan Chen, Tong Liu and 1 more

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mei DongDepartment of Cardiology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, 264000 Yantai, Shandong, China.
Lizhen WangDepartment of Cardiology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, 264000 Yantai, Shandong, China.
Gary TseTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, 300070 Tianjin, China.
Tao DaiDepartment of Cardiology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, 264000 Yantai, Shandong, China.
Tonglian LvTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, 300070 Tianjin, China.
Nan ZhangTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, 300070 Tianjin, China.
Lihong WangDepartment of Ultrasound, Affiliated Yantai Yuhuangding Hospital of Qingdao University, 264000 Yantai, Shandong, China.
Zhicheng XiaoDepartment of Cardiology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, 264000 Yantai, Shandong, China.
Tienan ChenDepartment of Cardiovascular Surgery, Second Hospital of Tianjin Medical University, 300070 Tianjin, China.
Tong LiuTianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, 300070 Tianjin, China.
Faxin RenDepartment of Cardiology, Affiliated Yantai Yuhuangding Hospital of Qingdao University, 264000 Yantai, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter aortic valve replacement (TAVR) is an effective alternative treatment for patients with aortic stenosis (AS) who have intermediate to high surgical risk or who are inoperable. However, the incidence of conduction abnormalities is high after TAVR, which can reduce the effectiveness of the surgery. Our research objective is to explore the risk factors of new-onset conduction abnormalities after TAVR, providing reference value for clinical doctors to better prevent and treat conduction abnormalities. Methods: Patients who underwent TAVR were divided into those who developed heart block and those who did not. Baseline clinical characteristics, cardiac structural parameters, procedural characteristics, electrocardiogram (ECG) changes before and after TAVR ( Results: We studied 93 patients, of whom 34.4% developed heart blocks. Univariate logistic regression showed that prior history of malignancy, atrial fibrillation, preoperative high-level total cholesterol and low-density lipoprotein cholesterol (LDL-C), Conclusions: Heart block is the most common complication of TAVR, and its significant independent risk factors include high-level LDL-C and

Indexed as

heart blockheart failurerisk factorssevere aortic stenosistranscatheter aortic valve replacement

Identifiers

PMID39076697
PMCPMC11266780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.