Evidence map›Paper›PMID 39076621›Full record

ArticleReviews in cardiovascular medicine2022

Association of Arterial Stiffness Indices with Framingham Cardiovascular Disease Risk Score.

Lin Jin, LanYue Tong, CuiQin Shen, LianFang Du, JianYing Mao, LiPing Liu, ZhaoJun Li

Abstract read
In one paragraph

Article in Reviews in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Ultrasound strain mapping of the non-aneurysmal abdominal aorta for detecting age-related aortic stiffening.International journal of cardiology. Cardiovascular risk and prevention · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lin JinDepartment of Ultrasound, Jiading District Central Hospital Affiliated Shanghai University of Medicine & Health Sciences, 201800 Shanghai, China.
LanYue TongDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, China.
CuiQin ShenDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, China.
LianFang DuDepartment of Ultrasound, Shanghai General Hospital, Shanghai Jiaotong University School of Medicine, 200080 Shanghai, China.
JianYing MaoDepartment of Ultrasound, Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, 200052 Shanghai, China.
LiPing LiuDepartment of Ultrasound, First Hospital of Shanxi Medical University, 030001 Taiyuan, Shanxi, China.
ZhaoJun LiDepartment of Ultrasound, Shanghai General Hospital Jiading Branch, Shanghai Jiaotong University School of Medicine, 201812 Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: The new non-invasive arterial stiffness indices, arterial velocity pulse index (AVI) and arterial pressure volume index (API) are known to be associated with cardiovascular disease risk. The present study aimed to examine the "dose-response" associations between AVI, API and Framingham cardiovascular disease risk score (FCVRS). Methods: This survey included individuals with arterial stiffness indices collected at age 18 years and older. We used Pearson's correlation coefficients and multivariate linear analyses to evaluate associations of AVI and API to other variables. The associations between FCVRS and AVI, API were analyzed by restrictive cubic spline. Results: 4311 people were included in the full study population, including 2091 males and 2220 females. In restricted cubic spline regression models, AVI or API had significant U-shaped associations with FCVRS, with the lowest risk score of cardiovascular disease was 8 units or 18 units, respectively. After AVI increased to 12 units, FCVRS increased rapidly until AVI was 27 units, and the FCVRS increased relatively flat afterward. For API, results were similar. When API increased to 23 units, the FCVRS increased rapidly, and after API was 52 units, FCVRS increased relatively flat. Conclusions: AVI or API had U-shaped associations with FCVRS. The associations may provide a new perspective for early treatment or lifestyle modifications to prevent cardiovascular diseases.

Indexed as

arterial pressure volume indexarterial stiffnessarterial velocity pulse indexFramingham score

Identifiers

PMID39076621
PMCPMC11266941

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.