Evidence map›Paper›PMID 39076426›Full record

ReviewReviews in cardiovascular medicine2023

Pulsed Field Ablation of Atrial Fibrillation: A Comprehensive Review.

Carlos D Matos, Carolina Hoyos, Andres F Miranda-Arboleda, Juan C Diaz, Daniela Hincapie, Carlos Patino, Ricardo H Hernadez, Paul C Zei, Jorge E Romero, Jose Osorio

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  6. Pulsed-field ablation versus thermal ablation in the management of atrial fibrillation: A narrative review.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carlos D MatosCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Carolina HoyosCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Andres F Miranda-ArboledaCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Juan C DiazCardiac Arrhythmia Center, Division of Cardiology, Las Vegas, Medellin 050021, Colombia.
Daniela HincapieCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Carlos PatinoCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Ricardo H HernadezHCA Electrophysiology, Mercy Hospital, Miami, FL 33133, USA.
Paul C ZeiCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Jorge E RomeroCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.
Jose OsorioCardiac Arrhythmia Service, Division of Cardiovascular Medicine, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulsed-field ablation (PFA) has emerged as a promising nonthermal ablation alternative for treating atrial fibrillation (AF). By delivering ultra-rapid high-energy electrical pulses, PFA induces irreversible electroporation, selectively targeting myocardial tissue while sparing adjacent structures from thermal or other damage. This article provides a comprehensive review of multiple pre-clinical studies, clinical studies, and clinical trials evaluating the safety, efficacy, and long-term outcomes of PFA in various settings and patient populations. Overall, the reviewed evidence highlights PFA's potential as a revolutionary ablation strategy for AF treatment. Offering comparable procedural efficacy to conventional ablation methods, PFA distinguishes itself with shorter procedure times and reduced risks of complications such as phrenic nerve palsy and potential esophageal injury. While further research is warranted to establish long-term efficacy, PFA's distinct advantages and evolving clinical evidence suggest a promising future for this novel nonthermal ablation approach. As PFA continues to advance, it has the potential to transform AF ablation procedures, providing a safer alternative for patients with atrial fibrillation.

Indexed as

atrial fibrillationcatheter ablationpulsed-field ablation

Identifiers

PMID39076426
PMCPMC11272841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.