ReviewReviews in cardiovascular medicine2022
Mitral Annular Disjunction: Pathophysiology, Pro-Arrhythmic Profile and Repair Pearls.
Review in Reviews in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Cardiac arrest secondary to mitral annular disjunction: a case report.European heart journal. Case reports · 2026Article
- Pronounced Mitral Annular Disjunction Is Associated With Increased Postoperative Palpitations After Mitral Valve Surgery for Barlow's Disease.Interdisciplinary cardiovascular and thoracic surgery · 2026Article
- Mitral Valve Surgery with and Without Mitral Annular Disjunction: A Meta-Analysis.Journal of cardiovascular development and disease · 2025Review
- Mitral Annular Disjunction: Epidemiology, Diagnostic Methods, Prognosis, and Novel Implications.Journal of cardiovascular development and disease · 2025Review
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitral annular disjunction (MAD) is a structural abnormality defined by a distinct separation of the mitral valve annulus-left atrial wall continuum and the basal aspect of the posterolateral left ventricle. This anomaly is often observed in patients with myxomatous mitral valve prolapse. Importantly, MAD has been strongly associated with serious ventricular arrhythmias and predisposes to sudden cardiac death. Therefore, we have to emphasize the need to diagnose this morphologic and functional abnormality in routine practice in order to facilitate optimal mitral valve repair and minimize patient risks. Nevertheless, clinical knowledge regarding MAD still remains limited. In the present review, we aim to shed light on several aspects of MAD, including distinct anatomical and pathophysiological characteristics, imaging modalities, association with ventricular arrhythmias, and current methods of treatment.
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Registered trials
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