Evidence map›Paper›PMID 39076228›Full record

ReviewReviews in cardiovascular medicine2022

Nonbacterial Thrombotic Endocarditis: Presentation, Pathophysiology, Diagnosis and Management.

Shahad Al Chalaby, Rakhee R Makhija, Ajay N Sharma, Muhammad Majid, Edris Aman, Sandhya Venugopal, Ezra A Amsterdam

Abstract readReview
In one paragraph

Review in Reviews in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shahad Al ChalabyAlameda Health System - Highland Hospital, Oakland, CA 94602, USA.
Rakhee R MakhijaDivision of Cardiovascular Medicine, University of California Davis, Davis, CA 95817, USA.
Ajay N SharmaSchool of Medicine, University of California Irvine, Irvine, CA 92697, USA.
Muhammad MajidDivision of Cardiovascular Medicine, University of California Davis, Davis, CA 95817, USA.
Edris AmanDivision of Cardiovascular Medicine, University of California Davis, Davis, CA 95817, USA.
Sandhya VenugopalDivision of Cardiovascular Medicine, University of California Davis, Davis, CA 95817, USA.
Ezra A AmsterdamDivision of Cardiovascular Medicine, University of California Davis, Davis, CA 95817, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Initially described in 1936, non-bacterial thrombotic endocarditis (NBTE) is a rare entity involving sterile vegetations on cardiac valves. These vegetations are usually small and friable, typically associated with hypercoagulable states of malignancy and inflammatory diseases such as systemic lupus erythematosus. Diagnosis remains challenging and is commonly made post-mortem although standard clinical methods such as echocardiography (transthoracic and transesophageal) and magnetic resonance imaging may yield the clinical diagnosis. Prognosis of NBTE is poor with very high morbidity and mortality usually related to the serious underlying conditions and high rates of systemic embolization. Therapeutic anticoagulation with unfractionated heparin has been described as useful for short term prevention of recurrent embolic events in patients with NBTE but there are no guidelines for management of this disease.

Indexed as

endocarditisLibman-Sacks endocarditismarantic endocarditisnonbacterial thrombotic endocarditis

Identifiers

PMID39076228
PMCPMC11273749

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.