Evidence map›Paper›PMID 39076207›Full record

ArticleFrontiers in aging neuroscience2024

Genetic link between

Wei Zheng, Ji He, Lu Chen, Weiyi Yu, Nan Zhang, Xiaoxuan Liu, Dongsheng Fan

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei ZhengDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Ji HeDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Lu ChenDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Weiyi YuDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Nan ZhangDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Xiaoxuan LiuDepartment of Neurology, Peking University Third Hospital, Beijing, China.
Dongsheng FanDepartment of Neurology, Peking University Third Hospital, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Genetics have been shown to have a substantial impact on amyotrophic lateral sclerosis (ALS). The ALS process involves defects in axonal transport and cytoskeletal dynamics. It has been identified that Methods: The analysis of whole-exome sequencing data from 1,068 patients was conducted to examine the genetic link between ALS and Results: In our cohort, the Conclusion: Our investigation revealed that mutations in the C-terminus of

Indexed as

amyotrophic lateral sclerosisaxonal transportcosegregation analysisKIF1AKIF5A

Identifiers

PMID39076207
PMCPMC11284166

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.