ArticleResearch in diagnostic and interventional imaging2023
Analysis on diagnostic failure of US-guided core needle biopsy for soft tissue tumors.
Article in Research in diagnostic and interventional imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Interpretable Deep Learning Radiomics Model for Preoperative Prediction of High-Grade Soft Tissue Sarcomas: A Multicenter MRI Study.Journal of imaging informatics in medicine · 2026Article
- Primary intracranial extraosseous Ewing's sarcoma with intraspinal metastasis in children: illustrative case.Journal of neurosurgery. Case lessons · 2025Article
- Inflammatory myofibroblastic tumors in children: a single-center retrospective study of clinical features, management, and outcomes.Frontiers in pediatrics · 2025Article
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8 authors.
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Abstract
Purpose: To evaluate the diagnostic yield of ultrasonography (US)-guided core needle biopsy (CNB) in the diagnosis of soft tissue tumors (STTs) and to analyze the failure factors. Methods: 139 patients with STTs that underwent both US-guided CNB and surgical resection were collected retrospectively. Compared with the histopathological results of surgical resection, the biopsy failure was defined as the following conditions: indefinitive diagnosis, including insufficient samples and unknown subtypes with correct biological potential classification; wrong diagnosis, including wrong biological potential classification and wrong subtypes with correct biological potential classification. Univariate and multivariate analyses from the perspectives of histopathological, demographic and US features together with biopsy procedures were performed to determine risk factors for diagnostic failure. Results: The diagnostic yield of US-guided CNB for STTs in our study was 78.4%, but when only considering the correct biological potential classification of STTs, the diagnostic yield was 80.6%. The multivariate analysis showed that adipocytic tumors (odds ratio (OR) = 10.195, 95% confidence interval (CI): 1.062 - 97.861, Conclusion: US-guided CNB can be an effective modality for the diagnosis of STTs. The diagnostic yield can be increased when the tumor vascular density was grade III in Color Doppler US, but can be decreased in adipocytic tumors, vascular tumors and masses with indeterminate US diagnosis.
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