Evidence map›Paper›PMID 39076100›Full record

ArticleCell transplantation

Effects of FGF2 Priming and Nrf2 Activation on the Antioxidant Activity of Several Human Dental Pulp Cell Clones Derived From Distinct Donors, and Therapeutic Effects of Transplantation on Rodents With Spinal Cord Injury.

Hidefumi Fukumitsu, Hitomi Soumiya, Kaito Nakamura, Kosuke Nagashima, Makoto Yamada, Hiroyuki Kobayashi, Takahiro Miwa, Atsuki Tsunoda, Tomoko Takeda-Kawaguchi, Ken-Ichi Tezuka and 1 more

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Article in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hidefumi FukumitsuLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.ORCID 0000-0002-9279-9344
Hitomi SoumiyaLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.
Kaito NakamuraLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.
Kosuke NagashimaLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.
Makoto YamadaLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.
Hiroyuki KobayashiLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.
Takahiro MiwaLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.
Atsuki TsunodaLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.
Tomoko Takeda-KawaguchiDepartment of Oral and Maxillofacial Surgery, Gifu University Graduate School of Medicine, Gifu, Japan.
Ken-Ichi TezukaDepartment of Stem Cell and Regenerative Medicine, Gifu University Graduate School of Medicine, Gifu, Japan.
Shoei FurukawaLaboratory of Molecular Biology, Department of Biofunctional Analysis, Gifu Pharmaceutical University, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the interest in cell transplantation therapy using human dental pulp cells (DPCs) has been increasing. However, significant differences exist in the individual cellular characteristics of human DPC clones and in their therapeutic efficacy in rodent models of spinal cord injury (SCI); moreover, the cellular properties associated with their therapeutic efficacy for SCI remain unclear. Here, using DPC clones from seven different donors, we found that most of the clones were highly resistant to H

Indexed as

AntioxidantsDental PulpFibroblast Growth Factor 2NF-E2-Related Factor 2Spinal Cord InjuriesAnimalsHeme Oxygenase-1HumansHydrogen PeroxideMaleMiceRatsRats, Sprague-DawleyAntioxidantsFibroblast Growth Factor 2Heme Oxygenase-1Hydrogen PeroxideNF-E2-Related Factor 2antioxidant factorsclonal differencehuman dental pulp cellsnuclear factor erythroid 2-related factor 2 (Nrf2) chemical activator (RTA402)spinal cord injury

Identifiers

PMID39076100
PMCPMC11289817

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.