Evidence map›Paper›PMID 39075372›Full record

Observational studyBMC surgery2024

Validation of the Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) scoring system for the diagnosis of acute appendicitis among Ethiopian patients: a multi-institutional observational study.

Abenezer Tarekegne Legesse, Segni Kejela, Abel Shiferaw Tesfaye, Meklit Solomon Gebremariam, Mihiret Abiy Hailu, Firehiwot Workneh, Tariku Mengesha Desalegn, Nathanael Fekadu Beyene

Abstract readObservational StudyMulticenter StudyValidation Study
In one paragraph

Observational study in BMC surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Global Emergency Medicine: A Scoping Review of the Literature From 2024.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abenezer Tarekegne LegesseFederal Ministry of Health Eka Kotebe General Hospital, Addis Ababa, Ethiopia. abenezerbln@gmail.com.
Segni KejelaAddis Ababa University, College of Health Science, Addis Ababa, Ethiopia.
Abel Shiferaw TesfayeAddis Ababa University, College of Health Science, Addis Ababa, Ethiopia.
Meklit Solomon GebremariamAddis Ababa University, College of Health Science, Addis Ababa, Ethiopia.
Mihiret Abiy HailuAddis Ababa University, College of Health Science, Addis Ababa, Ethiopia.
Firehiwot WorknehAddis Continental Institute of Public Health, Addis Ababa, Ethiopia.
Tariku Mengesha DesalegnSt. Peter Specialized Hospital, Addis Ababa, Ethiopia.
Nathanael Fekadu BeyeneICAP, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute appendicitis is the most common surgical emergency in Ethiopian clinical practice. Although a multitude of scoring systems have been used in clinical practice, none have been universally validated. The purpose of this study was to validate the Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA) scoring system in the Ethiopian context.

methodsA total of 315 consecutive patients who presented with a presumptive diagnosis of acute appendicitis and were planned to undergo appendectomy were studied. All the studied patients had diagnostic sonography and underwent the RIPASA scoring system. The sensitivity, specificity, positive predictive value, and negative predictive value of RIPASA and ultrasound results with intraoperative gross examinations.

resultsThe mean age of the participants was 27.4 ± 11.5 years, with a male-to-female ratio of 1.6:1. The concordance between ultrasound and RIPASA for the diagnosis of acute appendicitis was 93.6%. The sensitivity, specificity, positive predictive value, and negative predictive value of RIPASA were 96.2%, 30.8%, 93.9%, and 42.1%, respectively. Similarly, the sensitivity, specificity, positive predictive value, and negative predictive value of ultrasound were 95.3%, 27.8%, 95.6%, and 26.3%, respectively. White cell count and RIPASA scores were weakly correlated with intraoperative stages of acute appendicitis, r(313) = 0.18, p = 0.001, and r(313) = 0.129, p = 0.022, respectively. The rate of a negative appendectomy was 6%.

conclusionRIPASA and ultrasound had equivalent performance in the diagnosis of acute appendicitis. In both cases, the rate of negative appendectomy was low enough to validate RIPASA for clinical practice in low-income institutions where sonographic diagnosis by a conventionally trained radiologist is not available.

Indexed as

AppendectomyAppendicitisUltrasonographyAcute DiseaseAdolescentAdultEthiopiaFemaleHumansMaleMiddle AgedPredictive Value of TestsSensitivity and SpecificityYoung AdultAcute appendicitisLow-income-countriesRIPASA score

Identifiers

PMID39075372
PMCPMC11285438

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.