Evidence map›Paper›PMID 39075092›Full record

ArticleScientific reports2024

Copaiba oil's bactericidal activity and its effects on health and zootechnical performance for Nile tilapia after oral supplementation.

Nicoli Paganoti de Mello, Fernando Carlos Ramos Espinoza, Gustavo da Silva Claudiano, Jefferson Yunis-Aguinaga, Janaina Graça de Oliveira Carvalho, Josiane Elizabeth Almeida Silva, Elaine Cristina Pacheco de Oliveira, Julieta Rodini Engrácia de Moraes

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nicoli Paganoti de MelloPostgraduated Program in Aquaculture/Aquaculture Center of UNESP, Caunesp, Jaboticabal, , São Paulo, Brazil.
Fernando Carlos Ramos EspinozaPostgraduated Program in Aquaculture/Aquaculture Center of UNESP, Caunesp, Jaboticabal, , São Paulo, Brazil.
Gustavo da Silva ClaudianoInstitute of Biodversity and Forests, Federal University of Western Pará, UFOPA-IBEF, Rua Vera Paz, s/n (Unidade Tapajós) Bairro Salé, Santarém, PA, CEP 68040-255, Brazil. gsclaudiano@gmail.com.
Jefferson Yunis-AguinagaUniversidad Científica del Sur, Lima, Peru.
Janaina Graça de Oliveira CarvalhoPostgraduated Program in Aquaculture/Aquaculture Center of UNESP, Caunesp, Jaboticabal, , São Paulo, Brazil.
Josiane Elizabeth Almeida SilvaDepartment of Biological Sciences, Federal University of Amazonas, UFAM, Manaus, AM, Brazil.
Elaine Cristina Pacheco de OliveiraInstitute of Biodversity and Forests, Federal University of Western Pará, UFOPA-IBEF, Rua Vera Paz, s/n (Unidade Tapajós) Bairro Salé, Santarém, PA, CEP 68040-255, Brazil.
Julieta Rodini Engrácia de MoraesDepartment of Pathology, Theriogenology and One Health, Faculty of Agrarian and Veterinarian Sciences, São Paulo State University (UNESP), Jaboticabal, Brazil. julietaengracia@gmail.com.

Funding

CATECHOLAMINES AND REPRODUCTIVE AGINGR01AG002021 · NIA · UNIVERSITY OF FLORIDA · PI SIMPKINS, JAMES W. · 1985 to 1990
–
Conselho Nacional de Desenvolvimento Científico e Tecnológico 315157/2023-2Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001Fundação Amazônia de Amparo a Estudos e Pesquisas, FAPESPA 36/2021
6 · The paper itself

Abstract

Tilapia is one of the most important farmed fish in the world and the most cultivated in Brazil. The increase of this farming favors the appearance of diseases, including bacterial diseases. Therefore, the aim of this study was to evaluate the bactericidal activity of copaiba oil, Copaifera duckei, against Streptococcus agalactiae and Flavobacterium columnare and the dietary effect of copaiba oil on zootechnical performance, hematological, biochemical, immunological, and histological analysis before and after an intraperitoneal infection (body cavity) with S. agalactiae in Nile tilapia. For this, fish were randomly distributed into 15 fiber tanks in five treatments (0, 0.25, 0.50, 0.75, and 1.0%) and fed with a commercial diet supplemented with copaiba oil for 30 days. After this period, the fish were randomly redistributed for the experimental challenge with S. agalactiae into six treatments (T0, T1, T2, T3, T4, and T5), the fish were anesthetized, and blood samples were collected to assess hematological, biochemical, immunological, and histological parameters. Copaiba oil showed bactericidal activity against Streptococcus spp. and Flavobacterium spp. in vitro. In addition, concentrations of 0.75 and 1.0% of copaiba oil have an anti-inflammatory effect and improve hematological and immunological parameters, increasing leukocyte numbers, albumin, and serum lytic activity. Furthermore, there is an increase in the intestinal villus length and tissue damage in groups at concentrations of 0.75 and 1.0% of copaiba oil. In conclusion, copaiba oil presented bactericidal activity against Streptococcus spp. and Flavobacterium spp. in vitro, and oral supplementation at concentrations of 0.75 and 1.0% compared to the control group enhanced non-specific immune parameters and digestibility in Nile Tilapia.

Indexed as

CichlidsDietary SupplementsFish DiseasesFlavobacteriumStreptococcus agalactiaeAdministration, OralAnimal FeedAnimalsAnti-Bacterial AgentsAquacultureFabaceaeFlavobacteriaceae InfectionsPlant OilsStreptococcal InfectionsAnti-Bacterial AgentsPlant OilsFlavobacterium columnareImmunologyOreochromis niloticusPhytotherapyStreptococcus agalactiae

Identifiers

PMID39075092
PMCPMC11286787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.