ArticleNature communications2024
Modifiable lifestyle factors and the risk of post-COVID-19 multisystem sequelae, hospitalization, and death.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- β-Cell Dysfunction in COVID-19 and Post-COVID Syndrome: Molecular Mechanisms Linking Inflammation, Oxidative Stress, and Insulin Secretion.International journal of molecular sciences · 2026Review
- Association between dietary inflammatory index, empirical dietary inflammatory patterns and the risk of Long COVID: a prospective cohort study.BMC public health · 2026Article
- Age at Appendectomy, Pneumonia/Influenza Risk, and The Role of Modifiable Risk-factor Profiles.Journal of epidemiology and global health · 2026Article
- Impact of long COVID on diverse Australian populations: a multi-site, longitudinal prospective cohort study protocol.BMJ open · 2026Article
- A Chinese expert consensus on prostate-pelvic syndrome.Current urology · 2026Article
- Prognostic Value of Charlson Comorbidity Index in Patients with COVID-19.Tropical medicine and infectious disease · 2026Article
- Gut-Brain Axis Dysregulation in Inflammatory Bowel Disease: Implications for Coagulation Abnormalities and Extraintestinal Manifestations.International journal of general medicine · 2026Review
- Development and validation of a questionnaire to assess environmental and lifestyle factors influencing infectious disease outcomes: application to SARS-CoV-2-infected individuals in Cuba.Frontiers in public health · 2026Article
- Organ-specific proteomic aging clocks predict disease and longevity across diverse populations.Nature aging · 2026Article
- Long COVID in adults - a current review of the long-term health effects following SARS-CoV-2 infection.Journal of health monitoring · 2026Article
- Pre-pandemic lifestyle patterns and mental health outcomes among people reporting post-acute sequelae of COVID-19: evidence from a Slovenian population-based sample.BMC public health · 2025Article
- Review
- Sociodemographic factors, biomarkers and comorbidities associated with post-acute COVID-19 sequelae in UK Biobank.Nature communications · 2025Article
- Post-COVID Metabolic Fallout: A Growing Threat of New-Onset and Exacerbated Diabetes.Biomedicines · 2025Review
- A Comprehensive Scoping Review on Diet and Nutrition in Relation to Long COVID-19 Symptoms and Recovery.Nutrients · 2025Article
- Long COVID: A Systematic Review of Preventive Strategies.Infectious disease reports · 2025Review
- Unhealthy Food Consumption Is Associated with Post-Acute Sequelae of COVID-19 in Brazilian Elderly People.Infectious disease reports · 2025Article
- Role of Cardiovascular Health in the Bidirectional Progression Trajectories Between Cardiovascular Disease, Type 2 Diabetes, and Cancer.Journal of the American Heart Association · 2025Article
- Article
- National Trends in Asthma Prevalence among Adolescents in South Korea, 2007-2023: A National Representative Serial Study.International archives of allergy and immunology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Effective prevention strategies for post-COVID complications are crucial for patients, clinicians, and policy makers to mitigate their cumulative burden. This study evaluated the association of modifiable lifestyle factors (smoking, alcohol intake, BMI, physical activity, sedentary time, sleep duration, and dietary habits) with COVID-19 multisystem sequelae, death, and hospitalization in the UK Biobank cohort (n = 68,896). A favorable lifestyle (6-10 healthy factors; 46.4%) was associated with a 36% lower risk of multisystem sequelae (HR, 0.64; 95% CI, 0.58-0.69; ARR at 210 days, 7.08%; 95% CI, 5.98-8.09) compared to an unfavorable lifestyle (0-4 factors; 12.3%). Risk reductions spanned all 10 organ systems, including cardiovascular, coagulation, metabolic, gastrointestinal, kidney, mental health, musculoskeletal, respiratory disorders, and fatigue. This beneficial effect was largely attributable to direct lifestyle impacts independent of corresponding pre-infection comorbidities (71% for any sequelae). A favorable lifestyle was also related to the risk of post-COVID death (HR 0.59, 0.52-0.66) and hospitalization (HR 0.78, 0.73-0.84). These associations persisted across acute and post-acute infection phases, irrespective of hospitalization status, vaccination, or SARS-CoV-2 variant. These findings underscore the clinical and public health importance of adhering to a healthy lifestyle in mitigating long-term COVID-19 adverse impacts and enhancing future pandemic preparedness.
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