Evidence map›Paper›PMID 39074361›Full record

ArticleACS applied materials & interfaces2024

Dexamethasone Long-Term Controlled Release from Injectable Dual-Network Hydrogels with Porous Microspheres Immunomodulation Promotes Bone Regeneration.

Weikang Xu, Weihua Huang, Xiayu Cai, Zhaohui Dang, Lijing Hao, Liyan Wang

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. (Ca/Zn)COACS omega · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Weikang XuInstitute of Biological and Medical Engineering, Guangdong Academy of Sciences, No. 10 Shiliugang Road, Jianghai Avenue Central, Haizhu District, Guangzhou 510316, China.ORCID 0000-0001-6351-3944
Weihua HuangAffiliated Qingyuan Hospital, Guangzhou Medical University, Qingyuan People's Hospital, No. 35, Yinquan North Road, Qingcheng District, Qingyuan 511518, China.
Xiayu CaiInstitute of Biological and Medical Engineering, Guangdong Academy of Sciences, No. 10 Shiliugang Road, Jianghai Avenue Central, Haizhu District, Guangzhou 510316, China.
Zhaohui DangInstitute of Biological and Medical Engineering, Guangdong Academy of Sciences, No. 10 Shiliugang Road, Jianghai Avenue Central, Haizhu District, Guangzhou 510316, China.
Lijing HaoNational Engineering Research Centre for Human Tissue Restoration and Function Reconstruction, South China University of Technology, No. 381 Wushan Road, Guangzhou 510275, China.ORCID 0000-0003-2710-5112
Liyan WangDepartment of Stomatology, Foshan Women's and Children's Hospital, No. 11 Renmin Xi Road, Chancheng District, Foshan 528000, China.ORCID 0009-0002-5844-2381

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-lasting, controlled-release, and minimally invasive injectable platforms that provide a stable blood concentration to promote bone regeneration are less well developed. Using hexagonal mesoporous silica (HMS) loaded with dexamethasone (DEX) and poly(lactic-

Indexed as

Bone RegenerationDelayed-Action PreparationsDexamethasoneHydrogelsMesenchymal Stem CellsMicrospheresOsteogenesisAnimalsCell DifferentiationCell ProliferationImmunomodulationPolylactic Acid-Polyglycolic Acid CopolymerPorosityRatsRats, Sprague-DawleyDelayed-Action PreparationsDexamethasoneHydrogelsPolylactic Acid-Polyglycolic Acid Copolymerbone regenerationdrug-carrying porous microspheresdual-network hydrogelimmunomodulationlong-lasting controlled release

Identifiers

PMID39074361
PMCPMC11311136

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.