ArticleCirculation2024
General Capillary Endothelial Cells Undergo Reprogramming Into Arterial Endothelial Cells in Pulmonary Hypertension Through HIF-2α/Notch4 Pathway.
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Article in Circulation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18citing papers in PubMed
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Who cites it
18 citing papers in PubMed.
- Interpreting Pulmonary Hypertension Beyond Single Cells.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- E2F1 Drives Endothelial Arterial Programming in Pulmonary Arterial Hypertension.bioRxiv : the preprint server for biology · 2026Article
- Decoding spatial transcriptomics across multicellular and subcellular resolutions.Nature communications · 2026Article
- Transcriptional landscape of pulmonary artery endothelium reveals subpopulation- and disease-specific remodeling signatures.Communications biology · 2026Article
- Guidelines for evaluating endothelial function in vascular tissue.American journal of physiology. Heart and circulatory physiology · 2026Review
- From Heterogeneity to Plasticity: Endothelial Dynamics in Lung Disease.Pulmonary circulation · 2026Review
- Temporal Dynamics of Endothelium After Radiation Injury Reveal a Transient Pro-Angiogenic Capillary Subpopulation Associated with Skin Repair.International journal of molecular sciences · 2026Article
- Pericytes and Lung Vascular Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Endothelial Heterogeneity in Pulmonary Hypertension.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- eNAMPT/TLR4 signaling drives PAH cellular phenotypic switching and lung vascular remodeling.Cell communication and signaling : CCS · 2025Article
- Engineering HMGB1-derived Peptides to Unravel Sex-Specific Mechanisms in Pulmonary Arterial Hypertension.American journal of respiratory cell and molecular biology · 2025Article
- Genetic adaptations shaping survival, pregnancy, and life at high altitude and sea level.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Single-Cell and Spatial Transcriptomics Identified Fatty Acid-Binding Proteins Controlling Endothelial Glycolytic and Arterial Programming in Pulmonary Hypertension.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
- Lung endothelial cell heterogeneity in health and pulmonary vascular disease.American journal of physiology. Lung cellular and molecular physiology · 2025Review
- Notoginsenoside R1 Improved Hypoxic Pulmonary Hypertension by Inhibiting Glycolysis-Mediated Pulmonary Arterial Vascular Remodeling.Canadian respiratory journal · 2025Article
- Enhanced Spatial Transcriptomics Analysis of Mouse Lung Tissues Reveals Cell-Specific Gene Expression Changes Associated with Pulmonary Hypertension.Journal of respiratory biology and translational medicine · 2025Article
- Application of Spatial Omics in the Cardiovascular System.Research (Washington, D.C.) · 2025Review
- Charting the cellular landscape of pulmonary arterial hypertension through single-cell omics.Respiratory research · 2024Review
Corrections and comments
- Update of
Authors and funding
15 authors.
Bin LiuDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.ORCID 0000-0003-0467-3678
Dan YiDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.ORCID 0000-0002-2614-5027
Xiaomei XiaDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.ORCID 0009-0002-9679-4556
Karina RamirezDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.
Hanqiu ZhaoDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.
Yanhong CaoDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.
Ankit TripathiDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.ORCID 0009-0000-5019-2379
Ryan DongDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.
Anton GaoDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.
Hongxu DingDepartment of Pharmacy Practice & Science, College of Pharmacy (H.D.), University of Arizona, Tucson.ORCID 0000-0002-7846-9744
Shenfeng QiuDepartment of Basic Medical Science (S.Q.), College of Medicine-Phoenix, University of Arizona.ORCID 0000-0002-0730-1602
Vladimir V KalinichenkoPhoenix Children's Health Research Institute (V.V.K.), College of Medicine-Phoenix, University of Arizona.
You-Yang ZhaoProgram for Lung and Vascular Biology and Section for Injury Repair and Regeneration Research, Stanley Manne Children's Research Institute, Ann & Robert H. Lurie Children's Hospital of Chicago, IL (Y-Y.Z.).ORCID 0000-0002-0041-0339
Michael B FallonDepartment of Internal Medicine (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., M.B.F., Z.D.), College of Medicine-Phoenix, University of Arizona.ORCID 0000-0003-4087-803X
Zhiyu DaiDivision of Pulmonary, Critical Care and Sleep (B.L., D.Y., X.X., K.R., H.Z., Y.C., A.T., R.D., A.G., Z.D.), College of Medicine-Phoenix, University of Arizona.ORCID 0000-0002-2945-7923
Funding
Pulmonary Hypertension Breakthrough InitiativeR24HL123767 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI ALDRED, MICHEALA A, ERZURUM, SERPIL C. · 2014 to 2017
$10.1MNovel mechanisms of obliterative pulmonary vascular remodeling and sever pulmonary arterial hypertensionR01HL133951 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ZHAO, YOU-YANG · 2016 to 2024
$4.9MTranscriptional Regulation of Endothelial Cells after Neonatal Lung InjuryR01HL141174 · NHLBI · UNIVERSITY OF ARIZONA · PI Vladimir Kalinichenko · 2018 to 2026
$4.7MNovel alveolar mechanisms of hypoxemia in hepatopulmonary syndromeR01HL169509 · NHLBI · UNIVERSITY OF ARIZONA · PI Zhiyu Dai, MICHAEL B FALLON · 2023 to 2026
$3.0MGeneral Capillary to Arterial Endothelial Cell Transition in Pulmonary ArterialHypertensionR01HL170096 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2023 to 2026
$2.9MNegative regulators of endothelial regeneration in aging lungs and ARDSR01HL164014 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI ZHAO, YOU-YANG · 2022 to 2025
$2.7MNovel roles of RNA modifications in the pathogenesis of pulmonary vascular remodeling and PAHR01HL162299 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI ZHAO, YOU-YANG · 2022 to 2025
$2.6MRole of Endothelial SOX17 Deficiency in the Pathogenesis of Pulmonary HypertensionR01HL158596 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2022 to 2026
$2.3MNovel mechanisms of endothelial Injury in the pathogenesis of ARDSR01HL148810 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI ZHAO, YOU-YANG · 2020 to 2023
$2.3MNovel intrinsic endothelial stem cells responsible for lung endothelial regeneration and vascular repair in ARDSR01HL172447 · NHLBI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI YOU-YANG ZHAO · 2024 to 2026
$2.3MFatty acid-binding proteins sustain endothelial glycolysis and arterial programming in pulmonary arterial hypertensionR01HL162794 · NHLBI · WASHINGTON UNIVERSITY · PI Zhiyu Dai · 2023 to 2026
$2.3MRole of Smooth Muscle Progenitor Cells in Obliterative Vascular Remodeling and PHR00HL138278 · NHLBI · UNIVERSITY OF ARIZONA · PI DAI, ZHIYU · 2019 to 2021
$747kNHLBI NIH HHS R00 HL138278NHLBI NIH HHS R01 HL141174NHLBI NIH HHS R01 HL148810NHLBI NIH HHS R01 HL158596NHLBI NIH HHS R01 HL162299NHLBI NIH HHS R01 HL162794NHLBI NIH HHS R01 HL164014NHLBI NIH HHS R01 HL169509NHLBI NIH HHS R01 HL170096NHLBI NIH HHS R01 HL172447NHLBI NIH HHS R24 HL123767
Abstract
PubMed holds no abstract for this paper.
Indexed as
Basic Helix-Loop-Helix ProteinsEndothelial CellsHypertension, PulmonaryReceptor, Notch4Signal TransductionAnimalsCapillariesCellular ReprogrammingEndothelial PAS Domain-Containing Protein 1HumansMicePulmonary ArteryBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1Receptor, Notch4angiogenesisendotheliumlung vasculaturePAHright heart failure
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.