Evidence map›Paper›PMID 39074096›Full record

ArticlePloS one2024

The association between prolonged SARS-CoV-2 symptoms and work outcomes.

Arjun K Venkatesh, Huihui Yu, Caitlin Malicki, Michael Gottlieb, Joann G Elmore, Mandy J Hill, Ahamed H Idris, Juan Carlos C Montoy, Kelli N O'Laughlin, Kristin L Rising and 4 more

Abstract read
In one paragraph

Article in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Long COVID-19: A Concept Analysis.Infectious disease reports · 2025
    Article
  8. Article
  9. Article
  10. Observational
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Arjun K VenkateshDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America.ORCID https://orcid.org/0000-0002-8248-0567
Huihui YuCenter for Outcomes Research and Evaluation (CORE), Section of Cardiovascular Medicine, Yale School of Medicine, Connecticut, United State of America.
Caitlin MalickiDepartment of Emergency Medicine, Yale School of Medicine, New Haven, Connecticut, United States of America.
Michael GottliebDepartment of Emergency Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.
Joann G ElmoreDivision of General Internal Medicine and Health Services Research, David Geffen School of Medicine at the University of California, Los Angeles (UCLA), Los Angeles, California, United States of America.
Mandy J HillDepartment of Emergency Medicine, UTHealth Houston, Houston, Texas, United States of America.
Ahamed H IdrisDepartment of Emergency Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Juan Carlos C MontoyDepartment of Emergency Medicine, University of California, San Francisco, San Francisco, California, United States of America.
Kelli N O'LaughlinDepartments of Emergency Medicine and Global Health, University of Washington, Seattle, Washington, United States of America.
Kristin L RisingDepartment of Emergency Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.
Kari A StephensDepartment of Family Medicine, University of Washington, Seattle, Washington, United States of America.
Erica S SpatzDepartment of Epidemiology, Yale School of Public Health, New Haven, Connecticut, United States of America.
Robert A WeinsteinDivision of Infectious Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, Illinois, United States of America.ORCID https://orcid.org/0000-0002-3390-858X
INSPIRE Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While the early effects of the COVID-19 pandemic on the United States labor market are well-established, less is known about the long-term impact of SARS-CoV-2 infection and Long COVID on employment. To address this gap, we analyzed self-reported data from a prospective, national cohort study to estimate the effects of SARS-CoV-2 symptoms at three months post-infection on missed workdays and return to work. The analysis included 2,939 adults in the Innovative Support for Patients with SARS-CoV-2 Infections Registry (INSPIRE) study who tested positive for their initial SARS-CoV-2 infection at the time of enrollment, were employed before the pandemic, and completed a baseline and three-month electronic survey. At three months post-infection, 40.8% of participants reported at least one SARS-CoV-2 symptom and 9.6% of participants reported five or more SARS-CoV-2 symptoms. When asked about missed work due to their SARS-CoV-2 infection at three months, 7.2% of participants reported missing ≥10 workdays and 13.9% of participants reported not returning to work since their infection. At three months, participants with ≥5 symptoms had a higher adjusted odds ratio of missing ≥10 workdays (2.96, 95% CI 1.81-4.83) and not returning to work (2.44, 95% CI 1.58-3.76) compared to those with no symptoms. Prolonged SARS-CoV-2 symptoms were common, affecting 4-in-10 participants at three-months post-infection, and were associated with increased odds of work loss, most pronounced among adults with ≥5 symptoms at three months. Despite the end of the federal Public Health Emergency for COVID-19 and efforts to "return to normal", policymakers must consider the clinical and economic implications of the COVID-19 pandemic on people's employment status and work absenteeism, particularly as data characterizing the numerous health and well-being impacts of Long COVID continue to emerge. Improved understanding of risk factors for lost work time may guide efforts to support people in returning to work.

Indexed as

COVID-19SARS-CoV-2AbsenteeismAdultEmploymentFemaleHumansMaleMiddle AgedPandemicsProspective StudiesReturn to WorkSelf ReportUnited StatesYoung Adult

Identifiers

PMID39074096
PMCPMC11285965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.