Evidence map›Paper›PMID 39073671›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2024

Failure of ceftazidime/avibactam experimental therapy in the treatment of Klebsiella pneumoniae ST11 co-producing NDM-1 and OXA-48 carbapenemases infection.

Vajihe Sadat Nikbin, Elham Haj Agha Gholizadeh Khiavi, Mehdi Dehghani-Latani, Majid Hosseinzadeh, Mohammad Shirzadi, Samaneh Pourajam, Samereh Nouri, Hamid Solgi

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In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Multispecies emergence of dualAntimicrobial agents and chemotherapy · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Vajihe Sadat NikbinDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Elham Haj Agha Gholizadeh KhiaviDepartment of Bacteriology, Pasteur Institute of Iran, Tehran, Iran.
Mehdi Dehghani-LataniSchool of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Majid HosseinzadehDepartment of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Mohammad ShirzadiDepartment of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Samaneh PourajamDepartment of Internal Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
Samereh NouriInfectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Hamid SolgiIsfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran. hamid.solgi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Carbapenem-resistant organisms (CRO) represent a significant threat because of their widespread in hospital settings, difficult-to-treat, and association with high morbidity and mortality rates. Data on the efficacy of ceftazidime/avibactam (CAZ-AVI) among patients infected with CRO in Iran are lacking. Herein, we report a case of a 91-year-old man with infection caused by extensively drug-resistant ST11 co-harbouring bla

Indexed as

Anti-Bacterial AgentsAzabicyclo Compoundsbeta-LactamasesCeftazidimeKlebsiella InfectionsKlebsiella pneumoniaeAged, 80 and overBacterial ProteinsDrug CombinationsDrug Resistance, Multiple, BacterialFatal OutcomeHumansIranMaleMicrobial Sensitivity TestsTigecyclineAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo CompoundsBacterial Proteinsbeta-lactamase NDM-1beta-LactamasescarbapenemaseCeftazidimeDrug CombinationsoxacillinaseTigecyclineCeftazidime/avibactamExperimental treatmentST-11 carbapenem-resistant Klebsiella pneumonia

Identifiers

PMID39073671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.