Evidence map›Paper›PMID 39073653›Full record

ArticleDiscover nano2024

A novel transdermal drug delivery system: drug-loaded ROS-responsive ferrocene fibers for effective photoprotective and wound healing activity.

Sangwoo Kim, Yoon Kim, Chaehyun Kim, Won Il Choi, Byoung Soo Kim, Jinkee Hong, Hoik Lee, Daekyung Sung

Abstract read
In one paragraph

Article in Discover nano, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sangwoo Kim *Bio-Convergence Materials R&D Division, Center for Bio-Healthcare Materials, Korea Institute of Ceramic Engineering and Technology, 202 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.
Yoon Kim *Advanced Textile R&D Department, Research Institute of Convergence Technology, Korea Institute of Industrial Technology (KITECH), 143 Hanggaulro, Sangnok-gu, Ansan-si, Gyeonggi-do, 15588, Republic of Korea.
Chaehyun Kim *Bio-Convergence Materials R&D Division, Center for Bio-Healthcare Materials, Korea Institute of Ceramic Engineering and Technology, 202 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.
Won Il ChoiBio-Convergence Materials R&D Division, Center for Bio-Healthcare Materials, Korea Institute of Ceramic Engineering and Technology, 202 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.
Byoung Soo KimBio-Convergence Materials R&D Division, Center for Bio-Healthcare Materials, Korea Institute of Ceramic Engineering and Technology, 202 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea.
Jinkee HongDepartment of Chemical and Biomolecular Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Hoik LeeAdvanced Textile R&D Department, Research Institute of Convergence Technology, Korea Institute of Industrial Technology (KITECH), 143 Hanggaulro, Sangnok-gu, Ansan-si, Gyeonggi-do, 15588, Republic of Korea. hoik@kitech.re.kr.
Daekyung SungBio-Convergence Materials R&D Division, Center for Bio-Healthcare Materials, Korea Institute of Ceramic Engineering and Technology, 202 Osongsaengmyeong 1-ro, Osong-eup, Heungdeok-gu, Cheongju, Chungbuk, 28160, Republic of Korea. dksung@kicet.re.kr.

Funding

Korea Institute of Industrial Technology KITECH JB-24-0005the Korea Institute of Marine Science & Technology Promotion RS-2023-00254302the National Research Foundation of Korea 2021M3C1C3097647
6 · The paper itself

Abstract

The present study proposes an innovative transdermal drug delivery system using ferrocene-incorporated fibers to enhance the bioavailability and therapeutic efficacy of ascorbyl tetraisopalmitate. Using electrospinning technology, the authors created ferrocene polymer fibers capable of highly efficient drug encapsulation and controlled release in response to reactive oxygen species commonly found in wound sites. The approach improves upon previous methods significantly by offering higher drug loading capacities and sustained release, directly targeting diseased cells. The results confirm the potential of ferrocene fibers for localized drug delivery, potentially reducing side effects and increasing patient convenience. The method could facilitate the application of bioactive compounds in medical textiles and targeted therapy.

Indexed as

FerroceneFiberPhoto-protectivenessROS-responsivenessTransdermal drug delivery systemWound healing

Identifiers

PMID39073653
PMCPMC11286613

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.