Evidence map›Paper›PMID 39073518›Full record

Trial reportInternational journal of behavioral medicine2025

Assessing the Effectiveness of Multilevel Intervention Sequences on "Tension" Among Men Living with HIV: A Randomized-Control Trial.

Toan Ha, Hui Shi, Bang Nguyen Pham, Aidan Dsouza, Roman Shrestha, Suresh V Kuchipudi, Hung N Luu, Ngoan Tran Le, Stephen L Schensul

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in International journal of behavioral medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03746457 (Alcohol and ART Adherence), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03746457 nacompletednot on this map

Alcohol and ART Adherence: Assessment, Intervention and Modeling in India

TypeinterventionalSponsorUConn HealthRan2015 to 2018Enrolled940ConditionsAlcohol Consumption, HIV Infection PrimaryArmsBehavioral intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Enhancing quality of life through tailored interventions for men living with HIV.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Toan HaDepartment of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA, 15261, USA. toan.ha@pitt.edu.ORCID http://orcid.org/0000-0002-0574-0804
Hui ShiVanderbilt University Medical Center, Nashville, USA.
Bang Nguyen PhamPopulation Health and Demography Unit, Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea.
Aidan DsouzaVillanova University, Villanova, USA.
Roman ShresthaDepartment of Allied Health Sciences, University of Connecticut, Storrs, CT, USA.
Suresh V KuchipudiDepartment of Infectious Diseases and Microbiology, School of Public Health, University of Pittsburgh, 130 De Soto Street, Pittsburgh, PA, 15261, USA.
Hung N LuuDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA.
Ngoan Tran LeInstitute of Research and Development, Duy Tan University, Da Nang City, Vietnam.
Stephen L SchensulDepartment of Public Health Sciences, University of Connecticut School of Medicine, Farmington, CT, USA.

Funding

Alcohol and ART Adherence: Assessment, Intervention and Modeling in IndiaU01AA021990 · NIAAA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI SAGGURTI, NIRANJAN, SCHENSUL, JEAN J · 2014 to 2018
$3.4M
NIAAA NIH HHS U01-AA021990
6 · The paper itself

Abstract

backgroundTension (often times called "Tenshun" in Hindi) is a cultural expression used to convey feelings of distress and common mental disorders in India and among South Asia communities. This study compared the effectiveness of different intervention sequences in reducing tension among alcohol-consuming men living with HIV in India.

methodThis secondary data analysis paper utilized data from a randomized trial study titled "Alcohol and Antiretroviral Therapy (ART) Adherence: Assessment, Intervention, and Modeling in India." The multilevel interventions, including individual counseling (IC), group intervention (GI), and collective advocacy (CA), were conducted sequentially over three cycles at three ART centers. Additionally, another ART center, serving as a pilot site, received all three interventions simultaneously in the final cycle. Participants completed surveys assessing demographic characteristics, tension, and other variables including HIV stigma, a 4-day ART adherence, HIV symptoms, and depressive symptoms at four time points: baseline, 9 months, 18 months, and 24 months. General linear mixed models were employed to assess the intervention effects on tension.

resultsOut of 940 participants, 666 reported experiencing tension, including 54% reporting high tension. At site 1, the GI-CA-IC sequence resulted in a slope of -0.06, indicating that this sequence reduced tension from T1 to T4 compared to the control group (p < 0.01). Additionally, the pilot site where the intervention package was conducted simultaneously had a slope of -0.06, indicating that the intervention package also reduced tension compared to the control group (p < 0.01). Conversely, the CA-IC-GI sequence resulted in a slope of 0.07, indicating that this sequence resulted in significantly higher tension levels than the control group (p = 0.008) contrary to the expectation that the sequence would reduce tension.

conclusionThis study contributes valuable insights on the issue of tension among alcohol-consuming men living with HIV. The significant reduction in tension observed at the site using the GI-CA-IC sequence, which began with a group intervention, underscores the importance of intervention order and the importance of group intervention within multilevel intervention programs for tension reduction. Further research is needed to validate these observations and broaden our understanding of effective tension management strategies among people living with HIV in diverse settings.

trial registrationURL: clinicaltrials.gov. REGISTRATION NUMBER: NCT03746457.

Indexed as

HIV InfectionsStress, PsychologicalAdultCounselingDepressionHumansIndiaMaleMedication AdherenceMiddle AgedSocial StigmaHIVIndiaMental healthMultilevel interventionTension

Identifiers

PMID39073518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.