Evidence map›Paper›PMID 39073412›Full record

ReviewFuture oncology (London, England)2024

Clinical application of ctDNA in early diagnosis, treatment and prognosis of patients with non-small cell lung cancer.

Shenyu Zhu, Rongqian Wu, Xiangjin Liu, Bin Xie, Chunfa Xie, Shulin Li, Zhicheng Wu, Zuxiong Zhang, Zhixian Tang, Liang Gu

Abstract readReview
In one paragraph

Review in Future oncology (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shenyu ZhuDepartment of Thoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.ORCID 0000-0002-5897-9720
Rongqian WuDepartment of Endocrinology and Metabolism, Gaoxin Hospital of The First Affiliated Hospital of Nanchang University, Nanchang, China.ORCID 0009-0000-5430-8893
Xiangjin LiuDepartment of Thoracic Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.ORCID 0009-0004-6781-3089
Bin XieFirst Clinical Medical College, The Gannan Medical University, Ganzhou, China.
Chunfa XieDepartment of Thoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Shulin LiDepartment of Thoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Zhicheng WuDepartment of Thoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Zuxiong ZhangDepartment of Thoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Zhixian TangDepartment of Thoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.ORCID 0000-0001-6250-7139
Liang GuDepartment of Thoracic Surgery, The First Affiliated Hospital of Gannan Medical University, Ganzhou, China.ORCID 0009-0001-1703-3066

Funding

general projects of Jiangxi Traditional Chinese Medicine Science and Technology 2020B0214the National Health Commission Science and Technology Development Research Center 2019ZH-07E-003the National Natural Science Foundation of China 81860337, 81960326, and 82060384the Natural Science Foundation of Jiangxi Province 20202ACBL206014, 20192BAB205009, and 2020BABL20611the Science and Technology Programs of Jiangxi Health Commission 20201080 and 202130660
6 · The paper itself

Abstract

Lung cancer is one of the most common malignancies worldwide, with non-small cell lung cancer (NSCLC) being the most common type. As understanding of precise treatment options for NSCLC deepens, circulating tumor DNA (ctDNA) has emerged as a potential biomarker that has become a research hotspot and may represent a new approach for the individualized diagnosis and treatment of NSCLC. This article reviews the applications of ctDNA for the early screening of patients with NSCLC, guiding targeted therapy and immunotherapy, evaluating chemotherapy and postoperative efficacy, assessing prognosis and monitoring recurrence. With the in-depth study of the pathogenesis of NSCLC, plasma ctDNA may become an indispensable part of the precise treatment of NSCLC, which has great clinical application prospects.

Indexed as

Biomarkers, TumorCarcinoma, Non-Small-Cell LungCirculating Tumor DNAEarly Detection of CancerLung NeoplasmsHumansImmunotherapyMolecular Targeted TherapyPrognosisBiomarkers, TumorCirculating Tumor DNAcirculating tumor DNAeffect monitoringimmunotherapyminimal residual diseasenon-small cell lung cancertargeted therapy

Identifiers

PMID39073412
PMCPMC11514542

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.