ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024
Neurometabolic topography and associations with cognition in Alzheimer's disease: A whole-brain high-resolution 3D MRSI study.
Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Higher educational attainment, accelerated tau, and slower decline: unraveling the Alzheimer's paradox.European radiology · 2026Article
- Towards harmonized spectral quantification in MRSI: comparative analysis of backward-linear-predicted and originalMagma (New York, N.Y.) · 2026Article
- Dual association patterns between microglial activation and neuronal health in Alzheimer's disease: a whole-brain MRSI/PET study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Motion Correction in High-Resolution 3D Brain MRSI Without Water and Lipid Suppression.Magnetic resonance in medicine · 2026Article
- Phase Correction of MR Spectroscopic Imaging Data Using Model-Based Signal Estimation and Extrapolation.IEEE transactions on bio-medical engineering · 2026Article
- Creatine-weighted imaging in patients with Parkinson's disease.NPJ Parkinson's disease · 2025Article
- [Association between Tau protein deposition and brain metabolites: N-acetylaspartate and creatine as potential biomarkers for advanced Alzheimer's disease].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
- Spotlight on Alzheimer's disease and related dementias research in East Asia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Serum metabolomics identifies novel prognostic biomarkers inFrontiers in pharmacology · 2025Article
- Microglial TREM2 and cognitive impairment: insights from Alzheimer's disease with implications for spinal cord injury and AI-assisted therapeutics.Frontiers in cellular neuroscience · 2025Review
- Neurometabolic topography and associations with cognition in Alzheimer's disease: A whole-brain high-resolution 3D MRSI study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- High-resolution whole-brain magnetic resonance spectroscopic imaging in youth at risk for psychosis.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
introductionAltered neurometabolism, detectable via proton magnetic resonance spectroscopic imaging (
methodsWe used a novel whole-brain high-resolution
resultsProdromal AD and AD dementia patients exhibited spatially distinct reductions in N-acetylaspartate, and increases in myo-inositol. Reduced N-acetylaspartate and increased myo-inositol were associated with worse global cognitive performance, and N-acetylaspartate correlated with five specific cognitive scores. Neurometabolic topography provides biological insights into diverse cognitive dysfunctions. DISCUSSION: Whole-brain high-resolution HIGHLIGHTS: Whole-brain high-resolution
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.