Evidence map›Paper›PMID 39073141›Full record

ArticleHeadache2024

American Headache Society white paper on treatment of post-traumatic headache from concussion in youth.

Carlyn Patterson Gentile, Scott Rosenthal, Heidi Blume, Reena Gogia Rastogi, Jennifer McVige, Alma Bicknese, Ali Ladak, Harshul Zaveri, Kaitlin Greene, Karen Barlow

Abstract readConsensus Statement
In one paragraph

Article in Headache, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. NSAID Use Is Not Associated With Persisting Symptoms in Adolescent Concussion.Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine · 2026
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Carlyn Patterson GentileDivision of Pediatric Neurology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4996-2457
Scott RosenthalDepartment of Pediatrics - Neurology, Children's Hospital Colorado, Aurora, Colorado, USA.
Heidi BlumeDivision of Pediatric Neurology, Seattle Children's Hospital, University of Washington School of Medicine, Seattle, Washington, USA.
Reena Gogia RastogiDivision of Pediatric Neurology, Barrow Neurological Institute at Phoenix Children's Hospital, Phoenix, Arizona, USA.
Jennifer McVigePediatric Neurology, Pediatric and Adult Headache, Dent Neurologic Institute, Amherst, New York, USA.ORCID 0000-0002-0018-1644
Alma BickneseDivision of Pediatric Neurology, Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Ali LadakDivision of Pediatric Neurology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Harshul ZaveriDivision of Child Neurology, Children's Hospital of Orange County, UC Irvine School of Medicine, Orange, California, USA.
Kaitlin GreeneDivision of Pediatric Neurology, Oregon Health and Science University, Portland, Oregon, USA.
Karen BarlowChildren's Hospital and Health Services, University of Queensland, Brisbane, Queensland, Australia.ORCID 0000-0003-2612-8507

Funding

Trigeminovascular sensitization in post-traumatic headache: electrophysiologic and blood biomarkers in youthK23NS124986 · NINDS · CHILDREN'S HOSP OF PHILADELPHIA · PI Carlyn Anne Patterson Gentile · 2022 to 2026
$1.0M
NINDS NIH HHS K23 NS124986
6 · The paper itself

Abstract

objectiveTo provide healthcare professionals guidance on youth at risk for prolonged recovery and post-traumatic headache (PTH), and on pharmacologic and non-pharmacologic management of PTH due to concussion and mild traumatic brain injury.

backgroundHeadache is the most common persistent post-concussive symptom affecting 8% of youth for >3 months after concussion. Over the past decade, many studies have explored the treatment of PTH in youth, but there are no established guidelines.

methodsThis white paper is based on a synthesis of an updated systematic review of the literature on treatment of PTH and a narrative review of the literature on risk factors for prolonged recovery and health disparities. Results were interpreted by a group of expert providers in PTH in children and adolescents through collaboration of the PTH and pediatric special interest groups of the American Headache Society.

resultsFactors that consistently were associated with prolonged recovery from concussion and persistent PTH included female sex, a high number of acute symptoms, and adolescent age. Social determinants of health also likely play an important role in PTH and deserve consideration in the clinical and research settings. A total of 33 studies met the criteria for inclusion in the systematic review of PTH treatment in youth, although most were retrospective and of fair-to-poor quality. Treatment strategies included acute and preventive pharmacologic management, procedures, neuro-modulatory devices, physical therapy, physical activity, and behavioral health support. A collaborative care approach that includes a thoughtful combination of these management strategies is likely most effective.

conclusionsThis white paper provides a roadmap for tailoring the treatment of PTH based on factors influencing prolonged headache, the timing of therapies, and therapies with the most evidence for treating PTH in youth. We also highlight research needed for developing more definitive guidelines on PTH management in youth.

Indexed as

Brain ConcussionPost-Traumatic HeadacheAdolescentChildFemaleHumansMaleSocieties, MedicalSystematic Reviews as TopicUnited Statesconcussionpediatricpost‐traumatic headachetreatment

Identifiers

PMID39073141
PMCPMC11694339

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.