Evidence map›Paper›PMID 39073010›Full record

SynthesisClinical and translational medicine2024

A comprehensive overview of the molecular features and therapeutic targets in BRAF

Ruiqi Gu, Hongsheng Fang, Renjie Wang, Weixing Dai, Guoxiang Cai

Abstract readSystematic Review
In one paragraph

Synthesis in Clinical and translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruiqi GuDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Hongsheng FangDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Renjie WangDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0001-8856-8968
Weixing DaiDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.
Guoxiang CaiDepartment of Colorectal Surgery, Fudan University Shanghai Cancer Center, Shanghai, China.ORCID 0000-0003-2953-3460

Funding

Shanghai Municipal Health Commission 2022XD012Shanghai Municipal Hospital Development Center SHDC2022CRD046
6 · The paper itself

Abstract

As one of the most prevalent digestive system tumours, colorectal cancer (CRC) poses a significant threat to global human health. With the emergence of immunotherapy and target therapy, the prognosis for the majority of CRC patients has notably improved. However, the subset of patients with BRAF exon 15 p.V600E mutation (BRAF

Indexed as

Colorectal NeoplasmsProto-Oncogene Proteins B-rafHumansMolecular Targeted TherapyMutationBRAF protein, humanProto-Oncogene Proteins B-rafBRAFcolorectal cancermolecular featurestarget therapy

Identifiers

PMID39073010
PMCPMC11283586

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.