Evidence map›Paper›PMID 39072934›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2024

COVID-19 outcomes among patients with dementia and age-matched controls who were hospitalized in 21 US health-care systems.

Adrienne L Johnson, Nathaniel A Chin, Thomas M Piasecki, Karen L Conner, Timothy B Baker, Michael C Fiore, Wendy S Slutske

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adrienne L JohnsonCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.ORCID 0000-0002-6422-8173
Nathaniel A ChinDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.
Thomas M PiaseckiCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.
Karen L ConnerCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.
Timothy B BakerCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.
Michael C FioreCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.
Wendy S SlutskeCenter for Tobacco Research and Intervention, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA.

Funding

ADRD Prevention Messaging to Increase Smoking Cessation Attempts in Older Adult SmokersK23AG067929 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI JOHNSON, ADRIENNE L. · 2021 to 2025
$783k
National Institutes of Health-National Institute on Aging K23AG067929NCI NIH HHS 66590NIA NIH HHS K23 AG067929
6 · The paper itself

Abstract

introductionCOVID-19 had devastating impacts worldwide. However, most research examining the impact of dementia on COVID-19 outcomes has been conducted in Europe and Asia and has not examined dementia subtypes.

methodsA retrospective analysis of electronic health record data from 21 US health-care systems examined relationships of all-cause dementia, Alzheimer's disease (AD), and vascular dementia with in-hospital mortality, intensive care unit (ICU) admission, and hospital stay duration.

resultsAll-cause dementia, but not AD or vascular dementia independently, was associated with increased mortality risk, the inclusion of discharge to hospice as a mortality equivalent increased risk for mortality for all-cause dementia, and AD and vascular dementia. Patients with all-cause dementia and AD were less likely to be admitted to the ICU than patients without. Patients with any form of dementia had longer hospital stays than patients without. DISCUSSION: Dementia was associated with increased mortality or hospice discharge, decreased ICU admissions, and longer hospital stays. HIGHLIGHTS: Only all-cause dementia was associated with increased mortality risk. This risk was lower than what has been published in previous research. Combining mortality and hospice discharge increased risk for all dementia subtypes. All-cause and Alzheimer's disease (AD) dementia were associated with decreased intensive care unit admissions. All-cause, vascular, and AD dementia were associated with longer hospital stays.

Indexed as

COVID-19DementiaHospitalizationHospital MortalityLength of StayAgedAged, 80 and overAlzheimer DiseaseCase-Control StudiesDementia, VascularFemaleHumansIntensive Care UnitsMaleRetrospective StudiesSARS-CoV-2Alzheimer's diseaseCOVID‐19dementiaelectronic health recordsmortalityvascular dementia

Identifiers

PMID39072934
PMCPMC11497724

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.