Evidence map›Paper›PMID 39072870›Full record

ArticleBiochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology

An effective Caenorhabditis elegans CRISPR training module for high school and undergraduate summer research experiences in molecular biology.

Carmen Herrera Sandoval, Christopher Borchers, Scott T Aoki

Abstract read
In one paragraph

Article in Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. WormTagDB: A Systematic Survey of Endogenously Tagged Proteins inbioRxiv : the preprint server for biology · 2025
    Article
  3. ABCC11 Earwax Trait and Genotype Are Suitable Tools for Introductory Labs to Learn Genetics and Molecular Techniques.Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Carmen Herrera SandovalDepartment of Biochemistry and Molecular Biology, School of Medicine, Indiana University-Indianapolis, Indianapolis, Indiana, USA.
Christopher BorchersDepartment of Biochemistry and Molecular Biology, School of Medicine, Indiana University-Indianapolis, Indianapolis, Indiana, USA.ORCID 0000-0002-2887-2017
Scott T AokiDepartment of Biochemistry and Molecular Biology, School of Medicine, Indiana University-Indianapolis, Indianapolis, Indiana, USA.ORCID 0000-0002-1100-4600

Funding

Biochemistry in situ to determine inheritance of RNA-protein complexesR35GM142691 · NIGMS · INDIANA UNIVERSITY INDIANAPOLIS · PI AOKI, SCOTT T · 2021 to 2025
$2.0M
NIGMS NIH HHS 5R35GM142691NIGMS NIH HHS R35 GM142691School of Medicine, Indiana University
6 · The paper itself

Abstract

Engaging in research experiences as a high school or undergraduate student interested in science, technology, engineering, and mathematics (STEM) is pivotal for their academic and professional development. A structured teaching framework can help cultivate a student's curiosity and passion for learning and research. In this study, an eight-week training program was created to encompass fundamental molecular biology principles and hands-on laboratory activities. This curriculum focuses on using clustered regularly interspaced short palindromic repeats (CRISPR) gene editing in the Caenorhabditis elegans model organism. Through pre- and post-program assessments, enhancements in students' molecular biology proficiency and enthusiasm for scientific exploration were observed. Overall, this training module demonstrated its accessibility and ability to engage inexperienced students in molecular biology and gene editing methodologies.

Indexed as

Caenorhabditis elegansCurriculumMolecular BiologyStudentsAnimalsClustered Regularly Interspaced Short Palindromic RepeatsGene EditingHumansResearchSchoolsUniversitiesC. elegansCRISPRgene editingtraining module

Identifiers

PMID39072870
PMCPMC11568952

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.