Evidence map›Paper›PMID 39072288›Full record

ArticleBioactive materials2024

Lanqing Wang, Zi Mei, Guanyu Jin, Hao Liu, Shixian Lv, Runjia Fu, Muxing Li, Cuiping Yao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lanqing WangInstitute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, China.
Zi MeiSchool of Stomatology, School of Materials Science and Engineering, Department of General Surgery, Third Hospital, Peking University, Beijing, 100871, China.
Guanyu JinSchool of Stomatology, School of Materials Science and Engineering, Department of General Surgery, Third Hospital, Peking University, Beijing, 100871, China.
Hao LiuSchool of Stomatology, School of Materials Science and Engineering, Department of General Surgery, Third Hospital, Peking University, Beijing, 100871, China.
Shixian LvSchool of Stomatology, School of Materials Science and Engineering, Department of General Surgery, Third Hospital, Peking University, Beijing, 100871, China.
Runjia FuDepartment of Oncology, The Second Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250033, China.
Muxing LiSchool of Stomatology, School of Materials Science and Engineering, Department of General Surgery, Third Hospital, Peking University, Beijing, 100871, China.
Cuiping YaoInstitute of Biomedical Photonics and Sensing, School of Life Science and Technology, Key Laboratory of Biomedical Information Engineering of Ministry of Education, Xi'an Jiaotong University, Xi'an, 710049, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systematic administration of small molecular drugs often suffered from the low efficacy and systemic toxicity in cancer therapy. In addition, application of single mode drug usually leads to unsatisfactory therapeutic outcomes. Currently, developing multimodal-drug combination strategy that acts on different pathways without increasing side effects remains great challenge. Here, we developed a hydrogel system that co-delivered glycolysis inhibitor apigenin and chemo-drug gemcitabine to realize combination strategy for combating cancer with minimal systemic toxicity. We demonstrated that this system can not only eliminate tumor cells

Indexed as

Abscopal effectChitosan-based hydrogelControlled-releaseDrug deliveryPolymer carriers

Identifiers

PMID39072288
PMCPMC11276927

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.