Evidence map›Paper›PMID 39072243›Full record

ArticleTherapeutic advances in medical oncology2024

Fatigue in patients with metastatic breast cancer undergoing single-agent taxane-based chemotherapy: a real-world data global network.

Alessandra Fabi, Elizabeth M Gavioli, Renuka Wakade, Maria C Spera, Santiago Miracle, Neus Valveny, Elizabeth Butler, Maria DePizzol, Pier Adelchi Ruffini, Marcello Allegretti

Abstract read
In one paragraph

Article in Therapeutic advances in medical oncology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alessandra FabiPrecision Medicine Unit in Senology, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, P.le A. Gemelli n. 8, Rome 00168, Italy.
Elizabeth M GavioliDompé US, San Mateo, CA, USA.ORCID https://orcid.org/0000-0002-6436-0748
Renuka WakadeDompé US, San Mateo, CA, USA.
Maria C SperaDompé Farmaceutici S.p.A., L'Aquila, Italy.
Santiago MiracleRegulatory & Start-up, TFS HealthScience, Solna, Sweden.
Neus ValvenyRegulatory & Start-up, TFS HealthScience, Solna, Sweden.
Elizabeth ButlerDompé US, San Mateo, CA, USA.
Maria DePizzolDompé Farmaceutici S.p.A., Milan, Italy.
Pier Adelchi RuffiniDompé Farmaceutici S.p.A., Milan, Italy.
Marcello AllegrettiDompé Farmaceutici S.p.A., Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cancer-related fatigue (CRF) occurs in nearly all patients with metastatic breast cancer (MBC). Objectives: This real-world analysis aimed to describe the prevalence and importance of fatigue in patients with MBC within 3 months of treatment with single-agent taxane-based chemotherapy during the timeframe of 2020-2022 in the United States and Europe. It was also conducted to assess whether there was a difference in relapsed patients compared to patients diagnosed Design: Electronic health records were analyzed from approximately 150 million patients to identify patients with MBC who underwent taxane treatment. Results: In 2021, 50,490 patients had MBC, of whom 16,170 were diagnosed Conclusion: At least one in four patients with MBC undergoing taxane-based treatment will experience fatigue. This highlights the importance of validating screening tools to identify CRF, which is necessary to advance clinical trials aimed at investigating treatment strategies to improve patient-centered outcomes for fatigue.

Indexed as

breast cancercancer-related fatiguemetastatic breast cancertaxane

Identifiers

PMID39072243
PMCPMC11282541

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.