Evidence map›Paper›PMID 39072145›Full record

ReviewSynthetic and systems biotechnology2024

Advances in stress-tolerance elements for microbial cell factories.

Zheyi Kuang, Xiaofang Yan, Yanfei Yuan, Ruiqi Wang, Haifan Zhu, Youyang Wang, Jianfeng Li, Jianwen Ye, Haitao Yue, Xiaofeng Yang

Abstract readReview
In one paragraph

Review in Synthetic and systems biotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zheyi KuangSchool of Intelligence Science and Technology, Xinjiang University, Urumqi, 830017, China.
Xiaofang YanSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Yanfei YuanSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Ruiqi WangSchool of Intelligence Science and Technology, Xinjiang University, Urumqi, 830017, China.
Haifan ZhuSchool of Intelligence Science and Technology, Xinjiang University, Urumqi, 830017, China.
Youyang WangSchool of Intelligence Science and Technology, Xinjiang University, Urumqi, 830017, China.
Jianfeng LiSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Jianwen YeSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.
Haitao YueSchool of Intelligence Science and Technology, Xinjiang University, Urumqi, 830017, China.
Xiaofeng YangSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, 510006, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microorganisms, particularly extremophiles, have evolved multiple adaptation mechanisms to address diverse stress conditions during survival in unique environments. Their responses to environmental coercion decide not only survival in severe conditions but are also an essential factor determining bioproduction performance. The design of robust cell factories should take the balance of their growing and bioproduction into account. Thus, mining and redesigning stress-tolerance elements to optimize the performance of cell factories under various extreme conditions is necessary. Here, we reviewed several stress-tolerance elements, including acid-tolerant elements, saline-alkali-resistant elements, thermotolerant elements, antioxidant elements, and so on, providing potential materials for the construction of cell factories and the development of synthetic biology. Strategies for mining and redesigning stress-tolerance elements were also discussed. Moreover, several applications of stress-tolerance elements were provided, and perspectives and discussions for potential strategies for screening stress-tolerance elements were made.

Indexed as

ApplicationCell factoryResistance mechanismStress-tolerance elementsSynthetic biology

Identifiers

PMID39072145
PMCPMC11277822

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.