ArticleACS omega2024
Design Characteristics of a Neoteric, Superhydrophilic, Mechanically Robust Hydrogel Engineered To Limit Fouling in the Ocular Environment.
Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Engineering Drug-Eluting Ocular Bioadhesive "OcuTAPE" via Tannic Acid-Mediated Nanoparticle Bridging.Advanced functional materials · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Current challenges with ocular drug delivery and the chronic nature of many ocular ailments render the use of traditional ocular devices for additional drug delivery purposes very attractive. To achieve this feat, there is the need to develop biomaterials that are biocompatible, mechanically robust for ocular applications, highly transparent (depending on the targeted ocular device), and with ultralow protein adhesion potential (the primary step in processes that lead to fouling and potential device failure). Herein is reported the facile synthesis of a novel, highly transparent, mechanically robust, nontoxic, bulk functionalized hydrogel with characteristics suited to scalable fabrication of ocular implantable and nonimplantable devices. Synergistic superhydrophilicity between methacrylated poly(vinyl alcohol) (PVAGMA) and zwitterionic sulfobetaine methacrylate was exploited to obtain a superhydrophilic polymer conjugate through facile photoinitiated cross-linking polymerization. Proton nuclear magnetic resonance (
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Registered trials
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