Evidence map›Paper›PMID 39072090›Full record

ArticleACS omega2024

Initial Characterization of the Viridisins' Biological Properties.

Ross Rayne Vermeulen, Anton Du Preez van Staden, Tracey Ollewagen, Leonardo Joaquim van Zyl, Youran Luo, Wilfred A van der Donk, Leon Milner Theodore Dicks, Carine Smith, Marla Trindade

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ross Rayne VermeulenDepartment of Microbiology, Stellenbosch University, Matieland 7602, South Africa.ORCID https://orcid.org/0000-0002-2223-4364
Anton Du Preez van StadenExperimental Research Group, Faculty of Medicine and Health Sciences, Department of Medicine, Stellenbosch University, Francie van Zijl Drive, Parow 7499, South Africa.ORCID https://orcid.org/0000-0003-0596-8849
Tracey OllewagenExperimental Research Group, Faculty of Medicine and Health Sciences, Department of Medicine, Stellenbosch University, Francie van Zijl Drive, Parow 7499, South Africa.
Leonardo Joaquim van ZylInstitute for Microbial Biotechnology and Metagenomics, University of the Western Cape, Level 2 New Life Sciences Building, Robert Sobukwe Rd, Bellville 7535, South Africa.
Youran LuoDepartment of Chemistry and Howard Hughes Medical Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0002-8033-2472
Wilfred A van der DonkDepartment of Chemistry and Howard Hughes Medical Institute, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.ORCID https://orcid.org/0000-0002-5467-7071
Leon Milner Theodore DicksDepartment of Microbiology, Stellenbosch University, Matieland 7602, South Africa.ORCID https://orcid.org/0000-0002-5157-9046
Carine SmithExperimental Research Group, Faculty of Medicine and Health Sciences, Department of Medicine, Stellenbosch University, Francie van Zijl Drive, Parow 7499, South Africa.ORCID https://orcid.org/0000-0001-5924-9204
Marla TrindadeInstitute for Microbial Biotechnology and Metagenomics, University of the Western Cape, Level 2 New Life Sciences Building, Robert Sobukwe Rd, Bellville 7535, South Africa.ORCID https://orcid.org/0000-0002-2478-0270

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viridisin A1 and A2 were previously heterologously expressed, purified, and characterized as ribosomally produced and post-translationally modified lanthipeptides. Such lanthipeptide operons are surprisingly common in Gram-negative bacteria, although their expression seems to be predominantly cryptic under laboratory conditions. However, the bioactivity and biological role of most lanthipeptide operons originating from marine-associated

Identifiers

PMID39072090
PMCPMC11270710

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.