Evidence map›Paper›PMID 39072026›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Asymptomatic and mildly symptomatic influenza virus infections by season -- Case-ascertained household transmission studies, United States, 2017-2023.

Jessica E Biddle, Huong Q Nguyen, H Keipp Talbot, Melissa A Rolfes, Matthew Biggerstaff, Sheroi Johnson, Carrie Reed, Edward A Belongia, Carlos G Grijalva, Alexandra M Mellis

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Jessica E BiddleCenters for Disease Control and Prevention, Atlanta, Georgia.
Huong Q NguyenMarshfield Clinic Research Institute, Marshfield, Wisconsin.
H Keipp TalbotVanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0003-0141-1760
Melissa A RolfesCenters for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0002-0483-9941
Matthew BiggerstaffCenters for Disease Control and Prevention, Atlanta, Georgia.
Sheroi JohnsonCenters for Disease Control and Prevention, Atlanta, Georgia.
Carrie ReedCenters for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0001-7944-7638
Edward A BelongiaMarshfield Clinic Research Institute, Marshfield, Wisconsin.ORCID 0000-0001-7478-0415
Carlos G GrijalvaVanderbilt University Medical Center, Nashville, Tennessee.ORCID 0000-0002-2329-7797
Alexandra M MellisCenters for Disease Control and Prevention, Atlanta, Georgia.ORCID 0000-0001-6756-1425

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Household Transmission of Influenza Viruses in the Community-COVID 19 SupplementU01IP001083 · IP · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G, TALBOT, HELEN KEIPP · 2017 to 2019
$2.2M
Household Transmisson of Influenza Viruses in the CommunityU01IP001078 · IP · MARSHFIELD CLINIC RESEARCH FOUNDATION · PI NGUYEN, HUONG Q · 2017 to 2019
$2.0M
Mentoring in transmission of influenza and strategies for preventionK24AI148459 · NIAID · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GRIJALVA, CARLOS G · 2020 to 2024
$893k
ACL HHS U01IP001078ACL HHS U01IP001083NCATS NIH HHS UL1 TR002243NCIRD CDC HHS U01 IP001078NCIRD CDC HHS U01 IP001083NIAID NIH HHS K24 AI148459
6 · The paper itself

Abstract

Asymptomatic influenza virus infection occurs but may vary by factors such as age, influenza vaccination status, or influenza season. We examined the frequency of influenza virus infection and associated symptoms using data from two case-ascertained household transmission studies (conducted from 2017-2023) with prospective, systematic collection of respiratory specimens and symptoms. From the 426 influenza virus infected household contacts that met our inclusion criteria, 8% were asymptomatic, 6% had non-respiratory symptoms, 23% had acute respiratory symptoms, and 62% had influenza-like illness symptoms. Understanding the prevalence of asymptomatic and mildly symptomatic influenza cases is important for implementing effective influenza prevention strategies and enhancing the effectiveness of symptom-based surveillance systems.

Identifiers

PMID39072026
PMCPMC11275689

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.