Evidence map›Paper›PMID 39071865›Full record

ArticleAdvanced functional materials2024

Metabolically Glycoengineered Neural Stem Cells Boost Neural Repair After Cardiac Arrest.

Jian Du, Xiao Liu, Subash Marasini, Zhuoran Wang, Kris Dammen-Brower, Kevin J Yarema, Xiaofeng Jia

Abstract read
In one paragraph

Article in Advanced functional materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Building molecular CJournal of molecular modeling · 2026
    Article
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  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jian DuDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201.
Xiao LiuDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201.
Subash MarasiniDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201.
Zhuoran WangDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201.
Kris Dammen-BrowerDepartment of Biomedical Engineering, The Johns Hopkins School of Medicine, Baltimore, MD, 21205.
Kevin J YaremaDepartment of Biomedical Engineering, The Johns Hopkins School of Medicine, Baltimore, MD, 21205.
Xiaofeng JiaDepartment of Neurosurgery, University of Maryland School of Medicine, Baltimore, MD 21201.ORCID 0000-0003-1445-8525

Funding

Improving Brain Recovery Through GlycoengineeringR01NS125232 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI Xiaofeng Jia · 2022 to 2026
$2.0M
Brain Recovery after Cardiac Arrest with Metabolic Glycoengineered Stem CellsR01NS110387 · NINDS · UNIVERSITY OF MARYLAND BALTIMORE · PI JIA, XIAOFENG · 2018 to 2022
$1.7M
NINDS NIH HHS R01 NS110387NINDS NIH HHS R01 NS125232
6 · The paper itself

Abstract

Cardiac arrest (CA)-induced cerebral ischemia remains challenging with high mortality and disability. Neural stem cell (NSC) engrafting is an emerging therapeutic strategy with considerable promise that, unfortunately, is severely compromised by limited cell functionality after in vivo transplantation. This groundbreaking report demonstrates that metabolic glycoengineering (MGE) using the "Ac

Indexed as

cardiac arrestischemic brain injurymetabolic glycoengineeringneuroprotectionstem cell therapy

Identifiers

PMID39071865
PMCPMC11281434

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.