ArticlePlastic and reconstructive surgery. Global open2024
Perfusion Mapping of Flaps Using Indocyanine Green Fluorescence Angiography and Laser Speckle Contrast Imaging.
Article in Plastic and reconstructive surgery. Global open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Review
- A Novel Voxel-based Technique for 3-Dimensional Transparent Visualization of Lip-Nasal Vasculature.Plastic and reconstructive surgery. Global open · 2026Article
- Precision minimally invasive strategy for Hirschsprung's disease: from anatomical resection to whole-cycle functional management-a review.Frontiers in pediatrics · 2026Review
- Comparison of quantitative laser speckle contrast and indocyanine green imaging for intestinal perfusion measurements in robot assisted surgery.Scientific reports · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Indocyanine green fluorescence angiography (ICG-FA) is often used for assessing tissue circulation in reconstructive surgery. Indocyanine green (ICG) is injected intravenously and visualized in the tissue with an infrared camera. The information is used to plan the surgery, for example, in free flap breast reconstructions. Laser speckle contrast imaging (LSCI) is another method that uses laser to assess tissue perfusion in the skin. Unlike ICG-FA, LSCI is noninvasive and may therefore have an advantaged compared with ICG-FA. The aim of this study was to evaluate the correlation between information obtained from these two techniques. Methods: Five deep inferior epigastric perforator patients were included. The flaps were assessed with LSCI and ICG-FA. For LSCI, the perfusion was calculated in 32 regions of interest. For ICG-FA, the maximum slope and area under curve (AUC) were calculated based on average pixel intensity data. Results: Large variations in maximum slope values could be seen between flaps, whereas AUC had lower variability within the same flap and between flaps. Pearson rank correlation comparing average perfusion (LSCI) and AUC (ICG-FA) showed a correlation between the values (r = 0.55, Conclusions: There is a significant correlation between data obtained using LSCI and ICG-FA, when ICG-FA data are presented as AUC of the ICG-FA intensity curve. Maximum slope lacks significant correlation with flap data obtained with LSCI. The study indicates that LSCI may be used in reconstructive surgery to assess tissue circulation in a way similar to ICG-FA.
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