Evidence map›Paper›PMID 39071607›Full record

ArticleHeliyon2024

A pedigree analysis of Rotor hyperbilirubinemia combined with hepatitis B virus infection in a

Li-Zhen Lin, Qiu-Yan Wu, Jian-Hui Zhang, Shi-Jie Li, Wei-Zhen Wu, Dan-Dan Ruan, Min Wu, Qian Chen, Li-Sheng Liao, Zhu-Ting Fang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Li-Zhen LinDepartment of Traditional Chinese Medicine, the First Affiliated Hospital, Fujian Medical University, Fuzhou, 350005, China.
Qiu-Yan WuFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Jian-Hui ZhangFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Shi-Jie LiFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Wei-Zhen WuXiyuan Clinical Medical College of Beijing University of Chinese Medicine, Beijing, 100029, China.
Dan-Dan RuanFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Min WuFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Qian ChenFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Li-Sheng LiaoFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Zhu-Ting FangFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Jie-Wei LuoFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Zuo-An LiFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Zhou LiFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.
Hong LiFujian provincial hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, 350001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rotor syndrome (RS, OMIM#237450) is an extremely rare autosomal digenic recessive disorder characterized by mild non-hemolytic hereditary conjugated hyperbilirubinemia, caused by biallelic variation of Methods: One RS pedigree was recruited and clinical features were documented. Whole genome second-generation sequencing was used to screen candidate genes and mutations, Sanger sequencing confirmed predicted mutations. Results: This study detected a homozygous nonsense variant c.1738C > T (p.R580*) in the coding region of the Conclusion: The mutations may be the molecular genetic foundation for the presence of

Indexed as

Autosomal digenic recessive disorderHereditary conjugated hyperbilirubinemiaOATP1B1/B3Rotor syndromeSLCOB1SLCOB3

Identifiers

PMID39071607
PMCPMC11283089

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.