Evidence map›Paper›PMID 39071445›Full record

ArticlebioRxiv : the preprint server for biology2024

Direct piriform-to-auditory cortical projections shape auditory-olfactory integration.

Nathan W Vogler, Ruoyi Chen, Alister Virkler, Violet Y Tu, Jay A Gottfried, Maria N Geffen

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nathan W VoglerDepartment of Otorhinolaryngology, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0002-1526-3079
Ruoyi ChenDepartment of Otorhinolaryngology, Perelman School of Medicine, University of Pennsylvania.
Alister VirklerDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania.
Violet Y TuDepartment of Otorhinolaryngology, Perelman School of Medicine, University of Pennsylvania.
Jay A GottfriedDepartment of Neurology, Perelman School of Medicine, University of Pennsylvania.
Maria N GeffenDepartment of Otorhinolaryngology, Perelman School of Medicine, University of Pennsylvania.ORCID 0000-0003-3022-2993

Funding

Circuit Mechanisms of Sound Processing and Detection in the Auditory PathwayR01DC014479 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI GEFFEN, MARIA NEIMARK · 2015 to 2024
$4.7M
Neuronal circuits supporting learning-driven changes in auditory perception.R01DC015527 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI Maria Neimark Geffen · 2017 to 2026
$4.5M
Neuronal circuits for context-driven bias in auditory categorizationR01NS113241 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI COHEN, YALE E, GEFFEN, MARIA NEIMARK · 2019 to 2023
$3.5M
Neural mechanisms of multisensory auditory-olfactory integration in the auditory cortexF32MH127788 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI VOGLER, NATHAN · 2021 to 2023
$238k
NIDCD NIH HHS R01 DC014479NIDCD NIH HHS R01 DC015527NIMH NIH HHS F32 MH127788NINDS NIH HHS R01 NS113241
6 · The paper itself

Abstract

In a real-world environment, the brain must integrate information from multiple sensory modalities, including the auditory and olfactory systems. However, little is known about the neuronal circuits governing how odors influence and modulate sound processing. Here, we investigated the mechanisms underlying auditory-olfactory integration using anatomical, electrophysiological, and optogenetic approaches, focusing on the auditory cortex as a key locus for cross-modal integration. First, retrograde and anterograde viral tracing strategies revealed a direct projection from the piriform cortex to the auditory cortex. Next, using

Indexed as

auditoryauditory cortexmultisensory integrationolfactorypiriform cortex

Identifiers

PMID39071445
PMCPMC11275881

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.