Evidence map›Paper›PMID 39071296›Full record

ArticlebioRxiv : the preprint server for biology2024

Spatial constraints and cell surface molecule depletion structure a randomly connected learning circuit.

Emma M Thornton-Kolbe, Maria Ahmed, Finley R Gordon, Bogdan Sieriebriennikov, Donnell L Williams, Yerbol Z Kurmangaliyev, E Josephine Clowney

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Emma M Thornton-KolbeNeurosciences Graduate Program, University of Michigan Medical School, Ann Arbor, MI, USA.ORCID 0000-0002-3036-8071
Maria AhmedDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-0054-3315
Finley R GordonDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Bogdan SieriebriennikovDepartment of Biology, New York University, New York, NY, USA.ORCID 0000-0002-2948-7292
Donnell L WilliamsDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0001-5049-1539
Yerbol Z KurmangaliyevDepartment of Biology, Brandeis University, Waltham, MA, USA.ORCID 0000-0003-4829-2025
E Josephine ClowneyDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-9150-9464

Funding

Sensory Mechanisms and Disorders - Administrative SupplementT32DC000011 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Michael Thomas Roberts · 1989 to 2026
$9.5M
Generation and manipulation of combinatorial connectivity in olfactory perceptionR01DC018032 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Eleanor Josephine Clowney · 2020 to 2026
$2.7M
NIDCD NIH HHS R01 DC018032NIDCD NIH HHS T32 DC000011
6 · The paper itself

Abstract

The brain can represent almost limitless objects to "categorize an unlabeled world" (Edelman, 1989). This feat is supported by expansion layer circuit architectures, in which neurons carrying information about discrete sensory channels make combinatorial connections onto much larger postsynaptic populations. Combinatorial connections in expansion layers are modeled as randomized sets. The extent to which randomized wiring exists

Identifiers

PMID39071296
PMCPMC11275898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.