Evidence map›Paper›PMID 39071292›Full record

ArticlebioRxiv : the preprint server for biology2024

Dissecting human monoclonal antibody responses from mRNA- and protein-based XBB.1.5 COVID-19 monovalent vaccines.

Raianna F Fantin, Jordan J Clark, Hallie Cohn, Deepika Jaiswal, Bailey Bozarth, Alesandro Civljak, Vishal Rao, Igor Lobo, Jessica R Nardulli, Komal Srivastava and 11 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors.

Raianna F FantinDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jordan J ClarkDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Hallie CohnDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Deepika JaiswalDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Bailey BozarthDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Alesandro CivljakDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Vishal RaoDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Igor LoboDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jessica R NardulliDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Komal SrivastavaDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jeremy YongDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Robert Andreata-SantosDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kaitlyn BushfieldDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Edward S LeeDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, 06520, USA.
Gagandeep SinghDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
PVI Study Group
Steven H KleinsteinDepartment of Laboratory Medicine, Yale School of Medicine, New Haven, CT, 06520, USA.
Florian KrammerDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Viviana SimonDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Goran BajicDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Camila H CoelhoDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Funding

COLLABORATIVE INFLUENZA VACCINE INNOVATION CENTER: UNIVERSAL INFLUENZA VACCINE RESEARCH75N93019C00051 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KRAMMER, FLORIAN · 2019 to 2025
$105.4M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MARK Reid PHILIPS · 1985 to 2026
$83.1M
Conduits: Mount Sinai Health System Translational Science HubUL1TR004419 · NCATS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Rosalind J Wright · 2022 to 2026
$46.4M
NIH FIRST Cohort Cluster Hiring Initiative at Icahn School of Medicine at Mount SinaiU54CA267776 · NCI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Nihal Mohamed · 2021 to 2026
$17.4M
Viral Immunity and VAccination (VIVA) Human Immunology Project Consortium (HIPC)U19AI168631 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Ana Fernandez-Sesma · 2022 to 2026
$14.4M
Understanding antibody responses and defining correlates of protection for endemic and pandemic coronavirus strainsP01AI172531 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Florian Krammer · 2023 to 2026
$12.5M
Structural interrogation of vaccine- and infection-induced B cell responsesR01AI168178 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Goran Bajic · 2022 to 2026
$3.9M
COVID and Translational Science supercomputer (CATS)S10OD030463 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2021 to 2021
$2.0M
Big Omics Data Engine 2 SupercomputerS10OD026880 · OD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KOVATCH, PATRICIA · 2019 to 2019
$2.0M
NCATS NIH HHS UL1 TR004419NCI NIH HHS P30 CA016087NCI NIH HHS U54 CA267776NIAID NIH HHS 75N93019C00051NIAID NIH HHS P01 AI172531NIAID NIH HHS R01 AI168178NIAID NIH HHS U19 AI168631NIH HHS S10 OD026880NIH HHS S10 OD030463
6 · The paper itself

Abstract

The emergence of highly contagious and immune-evasive severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants has required reformulation of coronavirus disease 2019 (COVID-19) vaccines to target those new variants specifically. While previous infections and booster vaccinations can enhance variant neutralization, it is unclear whether the monovalent version, administered using either mRNA or protein-based vaccine platforms, can elicit

Indexed as

cryo-EMmonovalent XBB.1.5mRNA vaccinesNovavaxSARS-CoV-2 mAbs

Identifiers

PMID39071292
PMCPMC11275766

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.