Evidence map›Paper›PMID 39071282›Full record

ArticlebioRxiv : the preprint server for biology2024

Spatiotemporal transcriptomic profiling and modeling of mouse brain at single-cell resolution reveals cell proximity effects of aging and rejuvenation.

Eric D Sun, Olivia Y Zhou, Max Hauptschein, Nimrod Rappoport, Lucy Xu, Paloma Navarro Negredo, Ling Liu, Thomas A Rando, James Zou, Anne Brunet

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eric D SunDepartment of Biomedical Data Science, Stanford University, CA, USA.ORCID 0000-0001-8805-9864
Olivia Y ZhouDepartment of Genetics, Stanford University, CA, USA.
Max HauptscheinDepartment of Genetics, Stanford University, CA, USA.
Nimrod RappoportDepartment of Genetics, Stanford University, CA, USA.
Lucy XuDepartment of Genetics, Stanford University, CA, USA.
Paloma Navarro NegredoDepartment of Genetics, Stanford University, CA, USA.
Ling LiuDepartment of Neurology, Stanford University, CA, USA.
Thomas A RandoDepartment of Neurology, Stanford University, CA, USA.
James ZouDepartment of Biomedical Data Science, Stanford University, CA, USA.
Anne BrunetDepartment of Genetics, Stanford University, CA, USA.

Funding

Wnt signaling in muscle stem cell agingP01AG036695 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MARGARET A. GOODELL · 2011 to 2026
$29.3M
T cells in the aging brainR01AG071711 · NIA · STANFORD UNIVERSITY · PI BRUNET, ANNE · 2021 to 2025
$3.9M
Epigenetic Reprogramming of Cellular AgeR01AG071783 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RANDO, THOMAS A. · 2021 to 2025
$2.2M
NIA NIH HHS P01 AG036695NIA NIH HHS R01 AG071711NIA NIH HHS R01 AG071783
6 · The paper itself

Abstract

Old age is associated with a decline in cognitive function and an increase in neurodegenerative disease risk

Identifiers

PMID39071282
PMCPMC11275735

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.