Evidence map›Paper›PMID 39071174›Full record

ArticleBiofilm2024

A bacteriocin-based coating strategy to prevent vancomycin-resistant

Christian Kranjec, Jills Puthiaparambil Mathew, Kirill Ovchinnikov, Idowu Fadayomi, Ying Yang, Morten Kjos, Wen-Wu Li

Abstract read
In one paragraph

Article in Biofilm, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christian KranjecLaboratory of Microbial Gene Technology, Faculty of Chemistry, Biotechnology and Food Science. Norwegian University of Life Sciences, 1430, Ås, Norway.
Jills Puthiaparambil MathewSchool of Pharmacy and Bioengineering, Guy Hilton Research Centre, Keele University, Stoke-on-Trent, ST4 7QB, UK.
Kirill OvchinnikovLaboratory of Microbial Gene Technology, Faculty of Chemistry, Biotechnology and Food Science. Norwegian University of Life Sciences, 1430, Ås, Norway.
Idowu FadayomiSchool of Pharmacy and Bioengineering, Guy Hilton Research Centre, Keele University, Stoke-on-Trent, ST4 7QB, UK.
Ying YangSchool of Pharmacy and Bioengineering, Guy Hilton Research Centre, Keele University, Stoke-on-Trent, ST4 7QB, UK.
Morten KjosLaboratory of Microbial Gene Technology, Faculty of Chemistry, Biotechnology and Food Science. Norwegian University of Life Sciences, 1430, Ås, Norway.
Wen-Wu LiSchool of Pharmacy and Bioengineering, Guy Hilton Research Centre, Keele University, Stoke-on-Trent, ST4 7QB, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ever-increasing use of exogenous materials as indwelling medical devices in modern medicine offers to pathogens new ways to gain access to human body and begin, in some cases, life threatening infections. Biofouling of such materials with bacteria or fungi is a major concern during surgeries, since this is often associated with biofilm formation and difficult to treat, recalcitrant infections. Intense research efforts have therefore developed several strategies to shield the medical devices' surface from colonization by pathogenic microorganisms. Here, we used dopamine as a coupling agent to coat four different materials of medical interest (plastic polyetheretherketone (PEEK), stainless steel, titanium and silicone catheter) with the bacteriocins, enterocin EJ97-short and the thiopeptide micrococcin P1. Water contact angle measurements and x-ray photoelectron spectroscopy were used to verify the effective coating of the materials. The effect of bacteriocins coated on these materials on the biofilm formation by a vancomycin resistant

Indexed as

Antibiotic resistanceBacteriocinsBiofilmEnterococcus faeciumPEEKStainless steelTitaniumUrinary catheter

Identifiers

PMID39071174
PMCPMC11282937

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.