Evidence map›Paper›PMID 39070997›Full record

ReviewJournal of family medicine and primary care2024

Management of immune check-point inhibitor-associated colitis in patients with advanced metastatic cancers: A review article.

Abubakar Tauseef, Maryam Zafar, Sameed Abdul Hameed Siddiqui, Jalal Dufani, Bradley DeVrieze, Muazzam Mirza, Joseph Thirumalareddy, Akshat Sood, Mohsin Mirza

Abstract readReview
In one paragraph

Review in Journal of family medicine and primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Abubakar TauseefDepartment of Internal Medicine, Creighton University School of Medicine, United States.
Maryam ZafarGraduate of Dow University of Health Sciences, Pakistan.
Sameed Abdul Hameed SiddiquiGraduate of Dow University of Health Sciences, Pakistan.
Jalal DufaniHospitalist at Bergan Mercy Medical Center, United States.
Bradley DeVriezeDepartment of Internal Medicine, Creighton University School of Medicine, United States.
Muazzam MirzaHospitalist at Bergan Mercy Medical Center, United States.
Joseph ThirumalareddyHospitalist at Bergan Mercy Medical Center, United States.
Akshat SoodHospitalist at Bergan Mercy Medical Center, United States.
Mohsin MirzaDepartment of Internal Medicine, Creighton University School of Medicine, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune check-point inhibitors (ICPi) are immunomodulating agents, which have revolutionized the management of advanced metastatic cancers. Being immunomodulating agents, they are predisposed to causing colitis. This descriptive review article emphasized on the management of ICPi-associated colitis in advanced metastatic cancers. We used PubMed, Google Scholar, Scopus, and Embase databases for literature review, and terminologies commonly searched were "management," "immune check-point inhibitors," "colitis," "metastatic," "cancers," "literature," and "review." We reviewed a total of 11 articles done in the last 15 years relevant to ICPi colitis and its management; all the articles showed that diarrhea and colitis are the most common adverse effects observed in patients on ICPi, but prior to establishing the diagnosis of ICPi-causing colitis, possibility of

Indexed as

Check point inhibitorcolitisimmunemanagementmetastatic cancer

Identifiers

PMID39070997
PMCPMC11272031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.