ArticleOpen medicine (Warsaw, Poland)2024
Comparison of the ability of newly inflammatory markers to predict complicated appendicitis.
Article in Open medicine (Warsaw, Poland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Association of the Modified HALP Score with Disease Complexity in Deep Neck Infections: A Dual-Center Retrospective Study.Diagnostics (Basel, Switzerland) · 2026Article
- The utility of HALP, M-HALP, and the newly developed CANP scores in predicting prognosis of acute appendicitis.Updates in surgery · 2026Article
- Diagnostic utility of systemic inflammatory markers for acute cholecystitis in hemodialysis patients with end-stage renal disease.Medicine · 2026Article
- Diagnostic value of CAR, HALP, and SII for predicting complicated appendicitis: a reassessment of inflammatory indices.BMC surgery · 2026Article
- Development and validation of a diagnostic nomogram based on peripheral blood composite inflammatory markers for complicated acute appendicitis: a retrospective study.Frontiers in surgery · 2026Article
- The Role of Emerging Immune-Inflammatory Indexes in the Preoperative Differentiation of Complicated and Uncomplicated Acute Appendicitis: A Single-Center Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Comparative evaluation of the diagnostic value of HALP Score and systemic inflammatory immune index biomarkers in childhood appendicitis.Pakistan journal of medical sciences · 2025Article
- Predictive value of the HALP score in differentiating complicated and uncomplicated acute appendicitis.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Article
- PAN-Immune inflammation value: a new biomarker for diagnosing appendicitis in children??BMC pediatrics · 2025Article
- Delta neutrophil index, CRP/albumin ratio, procalcitonin, immature granulocytes, and HALP score in acute appendicitis: Best performing biomarker?Open medicine (Warsaw, Poland) · 2025Article
- Article
- Systemic inflammatory indices and age-dependent severity in acute appendicitis: a retrospective cohort study.Frontiers in immunology · 2025Article
- Development and validation of a nomogram for early prediction of sepsis-induced coagulopathy: a multicenter study.Frontiers in medicine · 2025Article
- Diagnostic Value of Systemic Immune Inflammation Index in Identifying Complicated Acute Appendicitis Cases.Cureus · 2024Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Acute appendicitis (AA) is the predominant condition responsible for acute abdominal pain across all age demographics. The purpose of this research is to determine if the hemoglobin, albumin, lymphocyte, and platelet (HALP) and modified HALP (m-HALP) scores differ between complicated and uncomplicated appendicitis in patients diagnosed with AA who have applied to the emergency department (ED). Additionally, this study aims to investigate whether HALP and m-HALP scores are superior to other biomarkers. Materials and methods: The retrospective analysis included adult patients, aged eighteen or older, who were diagnosed with AA, and sought treatment at the ED of a tertiary hospital. Patients were divided into two groups: complicated appendicitis (CA) and uncomplicated appendicitis (UCA). The cut-off in diagnostic value measurements was determined using the receiver operating characteristic analysis. Results: A total of 436 patients (CA: 126, UCA: 310) were included. Neutrophil-to-lymphocyte ratio (NLR), neutrophil-to-albumin ratio, systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and pan-immune inflammation value (PIV) were found to have acceptable diagnostic power in CA detection (area under the curve [AUC]: 0.735-0.783). In detecting UCA, HALP and m-HALP were of fair diagnostic power (AUC: 0.64, 0.68, respectively). Conclusions: In this study, we found that although PIV, SIRI, SII, and NLR had acceptable diagnostic values in distinguishing CA and UCA, HALP and m-HALP had fair diagnostic values.
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