Evidence map›Paper›PMID 39070800›Full record

Observational studyInternational journal of chronic obstructive pulmonary disease2024

Obesity Impact on Dyspnea in COPD Patients.

Alexis Dupuis, Aurore Thierry, Jeanne-Marie Perotin, Julien Ancel, Valérian Dormoy, Sandra Dury, Gaëtan Deslée, Claire Launois

Abstract readObservational Study
In one paragraph

Observational study in International journal of chronic obstructive pulmonary disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Association of Obesity with Symptoms and Quality of Life in COPD: Results from COSYCONET.International journal of chronic obstructive pulmonary disease · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Alexis DupuisDepartment of Respiratory Diseases, University Hospital of Reims, Reims, France.
Aurore ThierryUniversité de Reims Champagne-Ardenne, VieFra, CHU Reims, Unité d'Aide Méthodologique, Reims, F-51100, France.
Jeanne-Marie PerotinDepartment of Respiratory Diseases, University Hospital of Reims, Reims, France.ORCID 0000-0001-7184-3767
Julien AncelDepartment of Respiratory Diseases, University Hospital of Reims, Reims, France.ORCID 0000-0003-3128-9348
Valérian DormoyUniversity of Reims Champagne-Ardenne (URCA), Inserm UMR-S 1250, SFR Cap-Santé, Reims, France.ORCID 0000-0003-1725-371X
Sandra DuryDepartment of Respiratory Diseases, University Hospital of Reims, Reims, France.
Gaëtan DesléeDepartment of Respiratory Diseases, University Hospital of Reims, Reims, France.
Claire LaunoisDepartment of Respiratory Diseases, University Hospital of Reims, Reims, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The role of obesity on dyspnea in chronic obstructive pulmonary disease (COPD) patients remains unclear. We aimed to provide an assessment of dyspnea in COPD patients according to their Body Mass Index (BMI) and to investigate the impact of obesity on dyspnea according to COPD severity. Methods: One hundred and twenty seven COPD patients with BMI ≥ 18.5 kg/m² (63% male, median (interquartile range) post bronchodilator forced expiratory volume of 1 second (post BD FEV Results: Twenty-five percent of the patients were obese (BMI ≥ 30kg/m²), 66% of patients experienced disabling dyspnea (mMRC ≥ 2). mMRC scores did not differ depending on BMI categories (2 (1-3) for normal weight, 2 (1-3) 1 for overweight and 2 (1-3) for obese patients; p = 0.71). Increased mMRC scores (0-1 versus 2-3 versus 4) were associated with decreased post BD-FEV Conclusion: By contrast with non-obese patients, dyspnea did not increase with spirometric GOLD grades in obese patients. This might be explained by a reduced lung hyperinflation related to the mechanical effects of obesity and a less severe emphysema in severe COPD patients with obesity.

Indexed as

DyspneaObesityPulmonary Disease, Chronic ObstructiveAgedBody Mass IndexFemaleForced Expiratory VolumeHumansLungMaleMiddle AgedPulmonary EmphysemaRisk FactorsSeverity of Illness IndexSpirometryTomography, X-Ray Computedchronic obstructive pulmonary diseasedyspnealung functionobesitypulmonary emphysema

Identifiers

PMID39070800
PMCPMC11277818

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.