Evidence map›Paper›PMID 39070618›Full record

ArticleResearch square2024

Genome-wide analysis of TFIIB's role in termination of transcription.

Michael J O'Brien, Jared Schrader, Athar Ansari

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael J O'BrienDepartment of Biological Science, 5047 Gullen Mall, Wayne State University, Detroit, MI 48202.
Jared SchraderDepartment of Biological Science, 5047 Gullen Mall, Wayne State University, Detroit, MI 48202.
Athar AnsariDepartment of Biological Science, 5047 Gullen Mall, Wayne State University, Detroit, MI 48202.ORCID 0000-0003-2806-421X

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUNGE-MORRIS, MELISSA A · 2014 to 2021
$10.1M
Translational Research Support CoreP30ES036084 · NIEHS · WAYNE STATE UNIVERSITY · PI Melissa A Runge-Morris · 2024 to 2026
$5.2M
A new paradigm of general transcription factor TFIIB functionality in termination and promoter directionalityR01GM146803 · NIGMS · WAYNE STATE UNIVERSITY · PI Athar Imtiaz Ansari · 2022 to 2026
$1.6M
Orbitrap Velos with ETD for Wayne State ProteomicsS10OD010700 · OD · WAYNE STATE UNIVERSITY · PI STEMMER, PAUL M · 2012 to 2012
$575k
NCI NIH HHS P30 CA022453NIEHS NIH HHS P30 ES020957NIEHS NIH HHS P30 ES036084NIGMS NIH HHS R01 GM146803NIH HHS S10 OD010700
6 · The paper itself

Abstract

This study provides evidence that the role of TFIIB extends beyond initiation to include the termination step of transcription. Using GRO-seq analyses, we compared terminator readthrough phenotype in

Indexed as

Budding YeastGenome-wide AnalysesRNA polymerase IITFIIBTranscription

Identifiers

PMID39070618
PMCPMC11276024

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.