Evidence map›Paper›PMID 39070457›Full record

ArticleCureus2024

A Case of Fournier's Gangrene Following the Initiation of Dapagliflozin.

Natalie Shaykh, Avni Agrawal, Melville C O'Brien, Oshin Rai, Vanshika Tripathi, Vishal Jaikaransingh

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Dapagliflozin Beyond Glucose Lowering: Mechanisms of Renal and Systemic Protection.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Natalie ShaykhInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Avni AgrawalInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Melville C O'BrienInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Oshin RaiInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Vanshika TripathiInternal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Vishal JaikaransinghNephrology, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since being approved by the United States Food and Drug Administration (FDA) in 2013, sodium-glucose cotransporter-2 inhibitors (SGLT2is) have emerged as an appealing therapeutic choice for patients with diabetes due to their favorable effects on renal and cardiac health. Recent trials have further expanded the application of these drugs by showing a decrease in mortality rates among patients with both reduced and preserved ejection fraction heart failure, even in those without diabetes. Common adverse effects of SGLT2is include increased urinary frequency and urinary tract infections stemming from elevated glycosuria. Here, we present a case report involving a 66-year-old man who developed Fournier's gangrene (FG) shortly after initiating dapagliflozin - a rare but dangerous adverse effect associated with this medication.

Indexed as

dapagliflozinfournier's gangrene (fg)scrotal painsurgical intensive care unit (sicu)urology

Identifiers

PMID39070457
PMCPMC11272975

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.