Evidence map›Paper›PMID 39070361›Full record

ArticleCureus2024

Primary Testicular Extranodal NK/T-cell Lymphoma Nasal Type Associated With Epstein-Barr Virus Infection: A Moroccan Case Report.

Hanaa Nejjari, Intissar Ait Zine, Wafa Ammouri, Zakia Bernousssi, Hakima Kabbaj

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hanaa NejjariCentral Laboratory of Virology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Intissar Ait ZineInternal Medecine Department, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Wafa AmmouriInternal Medecine Department, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Zakia BernousssiPathology Department, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.
Hakima KabbajCentral Laboratory of Virology, Ibn Sina Hospital, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epstein-Barr virus (EBV) is a ubiquitous and potentially oncogenic human herpesvirus. In this article, we discuss a rare case of primary testicular NK/T-cell lymphoma, nasal type, associated with high plasma Epstein-Barr virus DNA load. The patient, a 45-year-old man, presented with painful testicular swelling, fever, and weight loss. An orchiectomy revealed tumor proliferation, which was diagnosed as testicular NK/T cell lymphoma, nasal type, confirmed by immunohistochemistry, and classified as stage IV according to the Ann Arbor classification. The patient was treated with SMILE chemotherapy. After treatment, a PET scan showed complete remission with negative EBV DNA levels. The discussion focused on the role of EBV in the development of this malignant lymphoproliferation and the importance of quantifying EBV DNA load by real-time PCR in assessing prognosis, patient follow-up, and response to treatment.

Indexed as

epstein-barr virusextranodal nk-t-celllymphomareal-time pcrtestis

Identifiers

PMID39070361
PMCPMC11283753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.