Evidence map›Paper›PMID 39070267›Full record

ReviewFrontiers in microbiology2024

Artificial intelligence tools for the identification of antibiotic resistance genes.

Isaac Olatunji, Danae Kala Rodriguez Bardaji, Renata Rezende Miranda, Michael A Savka, André O Hudson

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Review
  3. Metabolism-Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Carbapenem-ResistantAntibiotics (Basel, Switzerland) · 2025
    Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isaac OlatunjiThomas H. Gosnell School of Life Sciences, College of Science, Rochester Institute of Technology, Rochester, NY, United States.
Danae Kala Rodriguez BardajiThomas H. Gosnell School of Life Sciences, College of Science, Rochester Institute of Technology, Rochester, NY, United States.
Renata Rezende MirandaSchool of Chemistry and Materials Science, College of Science, Rochester Institute of Technology, Rochester, NY, United States.
Michael A SavkaThomas H. Gosnell School of Life Sciences, College of Science, Rochester Institute of Technology, Rochester, NY, United States.
André O HudsonThomas H. Gosnell School of Life Sciences, College of Science, Rochester Institute of Technology, Rochester, NY, United States.

Funding

Isolation, identification and characterization of potentially novel antibiotics from rhizospheric bacteria without detectable in vitro resistanceR15GM144862 · NIGMS · ROCHESTER INSTITUTE OF TECHNOLOGY · PI HUDSON, ANDRE O · 2021 to 2022
$544k
NIGMS NIH HHS R15 GM144862
6 · The paper itself

Abstract

The fight against bacterial antibiotic resistance must be given critical attention to avert the current and emerging crisis of treating bacterial infections due to the inefficacy of clinically relevant antibiotics. Intrinsic genetic mutations and transferrable antibiotic resistance genes (ARGs) are at the core of the development of antibiotic resistance. However, traditional alignment methods for detecting ARGs have limitations. Artificial intelligence (AI) methods and approaches can potentially augment the detection of ARGs and identify antibiotic targets and antagonistic bactericidal and bacteriostatic molecules that are or can be developed as antibiotics. This review delves into the literature regarding the various AI methods and approaches for identifying and annotating ARGs, highlighting their potential and limitations. Specifically, we discuss methods for (1) direct identification and classification of ARGs from genome DNA sequences, (2) direct identification and classification from plasmid sequences, and (3) identification of putative ARGs from feature selection.

Indexed as

antibiotic resistanceantibiotic resistance genesartificial intelligencedeep learningHidden Markov Modelrandom forestsupport vector machines

Identifiers

PMID39070267
PMCPMC11272472

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.