Evidence map›Paper›PMID 39069687›Full record

ArticleClinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology2024

Investigating the Relationship of Serum CD163, YKL40 and VILIP-1 Levels with Autism Severity and Language-cognitive Development in Preschool Children with Autism.

Samet Can Demirci, Süreyya Barun, Ahmet Özaslan, Özlem Gülbahar, Tuba Saadet Deveci Bulut, Aysu Duyan Çamurdan, Elvan İşeri

Abstract read
In one paragraph

Article in Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samet Can DemirciDepartment of Child and Adolescent Psychiatry, Gazi University Medical Faculty, Ankara, Turkey.ORCID https://orcid.org/0000-0002-8158-900X
Süreyya BarunDepartment of Medical Pharmacology, Gazi University Medical Faculty, Ankara, Turkey.ORCID https://orcid.org/0000-0003-3726-8177
Ahmet ÖzaslanDepartment of Child and Adolescent Psychiatry, Gazi University Medical Faculty, Ankara, Turkey.ORCID https://orcid.org/0000-0001-7741-201X
Özlem GülbaharDepartment of Medical Biochemistry, Gazi University Medical Faculty, Ankara, Turkey.ORCID https://orcid.org/0000-0003-0450-4305
Tuba Saadet Deveci BulutDepartment of Medical Biochemistry, Gazi University Medical Faculty, Ankara, Turkey.ORCID https://orcid.org/0000-0002-3023-919X
Aysu Duyan ÇamurdanDepartment of Child Health and Diseases, Gazi University Medical Faculty, Ankara, Turkey.ORCID https://orcid.org/0000-0001-8384-7423
Elvan İşeriDepartment of Child and Adolescent Psychiatry, Gazi University Medical Faculty, Ankara, Turkey.ORCID https://orcid.org/0000-0002-1809-5867

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to compare serum levels of CD163, YKL-40, and VILIP-1 between children with autism spectrum disorder (ASD) and healthy controls, while also investigating their association with the severity of ASD and language development. Methods: The study included 40 ASD-diagnosed patients (aged 18-72 months) and 40 age-matched healthy controls. Childhood Autism Rating Scale, Preschool Language Scale-4, and Ankara Development Screening Inventory were administered to children in the ASD group. Serum CD163, YKL-40 and VILIP-1 levels were measured with an enzyme- linked immunosorbent assay kit. Results: In the ASD group compared to the control group, serum VILIP-1 levels were significantly higher ( Conclusion: Our findings highlight that the levels of CD163 and YKL-40 significantly predicted ASD severity, indicating a potential role of neuroinflammation in the development of ASD.

Indexed as

Autism spectrum disorderChitinase-3-like protein 1NeurocalcinNeuroinflammation

Identifiers

PMID39069687
PMCPMC11289611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.