Evidence map›Paper›PMID 39069597›Full record

ArticleScientific reports2024

Field evaluation of a volatile pyrethroid spatial repellent and etofenprox treated clothing for outdoor protection against forest malaria vectors in Cambodia.

Élodie A Vajda, Amanda Ross, Dyna Doum, Emma L Fairbanks, Nakul Chitnis, Jeffrey Hii, Sarah J Moore, Jason H Richardson, Michael Macdonald, Siv Sovannaroth and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Making scents of mosquito repellents.Trends in parasitology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Élodie A VajdaUniversity of California, San Francisco, 550 16th Street, San Francisco, CA, 94158, USA. elodie.vajda@ucsf.edu.
Amanda RossSwiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland.
Dyna DoumUniversity of California, San Francisco, 550 16th Street, San Francisco, CA, 94158, USA.
Emma L FairbanksSwiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland.
Nakul ChitnisSwiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland.
Jeffrey HiiUniversity of California, San Francisco, 550 16th Street, San Francisco, CA, 94158, USA.
Sarah J MooreSwiss Tropical and Public Health Institute, Socinstrasse 57, 4002, Basel, Switzerland.
Jason H RichardsonInnovative Vector Control Consortium, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, Merseyside, L3 5QA, UK.
Michael MacdonaldInnovative Vector Control Consortium, Liverpool School of Tropical Medicine, Pembroke Place, Liverpool, Merseyside, L3 5QA, UK.
Siv SovannarothNational Center for Parasitology, Entomology and Malaria Control, 477, Phnom Penh, Cambodia.
Pen KimhengDepartment of Health of Mondulkiri, C5XX+CP4, 76, Krong Saen Monourom, Cambodia.
David J McIverUniversity of California, San Francisco, 550 16th Street, San Francisco, CA, 94158, USA.
Allison TatarskyUniversity of California, San Francisco, 550 16th Street, San Francisco, CA, 94158, USA.
Neil F LoboUniversity of California, San Francisco, 550 16th Street, San Francisco, CA, 94158, USA.

Funding

Australia Department of Foreign Affairs and Trade (DFAT) through the Innovative Vector Control Consortium A134328
6 · The paper itself

Abstract

Cambodia's goal to eliminate malaria by 2025 is challenged by persistent transmission in forest and forest fringe areas, where people are exposed to Anopheles mosquito bites during the day and night. Volatile pyrethroid spatial repellents (VPSRs) and insecticide-treated clothing (ITC) could address these gaps. This study evaluated the outdoor application of one passive transfluthrin-based VPSR, four etofenprox-ITCs paired with a picaridin topical repellent, and a combination of VPSR and ITC against wild Anopheles landing in Cambodia. A 7 × 7 Latin-square study was conducted over 49 collection nights in temporary open structures in Mondulkiri Province. All interventions substantially reduced Anopheles landing, with protective efficacy ranging from 61 to 95%. Mathematical modeling showed significant reductions in vectoral capacity, especially with the combined ITC and VPSR and VPSR alone, albeit with decreased effectiveness over time. These interventions have the potential to reduce outdoor and daytime Anopheles biting, offering valuable contributions to malaria elimination efforts in Cambodia and the Greater Mekong Subregion, contingent upon achieving effective coverage and adherence.

Indexed as

AnophelesForestsInsect RepellentsMalariaMosquito ControlMosquito VectorsPyrethrinsAnimalsCambodiaCyclopropanesFluorobenzenesHumansInsect Bites and StingsInsecticides(2,3,5,6-tetrafluoro-4-methoxymethylphenyl)methyl-2,2-dimethyl-3-(1-propenyl)cyclopropanecarboxylateCyclopropanesFluorobenzenesInsecticidesInsect RepellentsPyrethrins

Identifiers

PMID39069597
PMCPMC11284218

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.