Evidence map›Paper›PMID 39069575›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Management of uncontrolled/recurrent epistaxis by ligation or cauterization of the sphenopalatine artery: a scoping review.

Francesco Dispenza, Francesco Lorusso, Salvatore Alberto Di Vincenzo, Anita Dolce, Angelo Immordino, Salvatore Gallina, Antonino Maniaci, Jerome Rene Lechien, Christian Calvo-Henriquez, Alberto Maria Saibene and 1 more

Registry-linked trialAbstract readScoping Review
PubMed Full text at PMC Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07421622 (A Pilot Randomized Controlled Trial in Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen Block), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07421622 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

A Pilot Randomized Controlled Trial in Management of Epistaxis Comparing Nasal Packing Versus Greater Palatine Foramen Block

TypeinterventionalSponsorSheikh Zayed Federal Postgraduate Medical InstituteRan2026 to 2027Enrolled40ConditionsEpistaxis Nosebleed, Greater Palatine ForamenArmsGreater Palatine Foramen Block with 2% xylocaine with adrenaline, Anterior Nasal Packing
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco DispenzaOtorhinolaringology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Azienda Ospedaliera Universitaria Policlinico ''Paolo Giaccone'', University of Palermo, Via del Vespro, 133, Palermo, 90127, Italy.ORCID https://orcid.org/0000-0002-5844-9762
Francesco LorussoOtorhinolaringology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Azienda Ospedaliera Universitaria Policlinico ''Paolo Giaccone'', University of Palermo, Via del Vespro, 133, Palermo, 90127, Italy.ORCID https://orcid.org/0000-0002-2120-5852
Salvatore Alberto Di VincenzoOtorhinolaringology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Azienda Ospedaliera Universitaria Policlinico ''Paolo Giaccone'', University of Palermo, Via del Vespro, 133, Palermo, 90127, Italy.
Anita DolceOtorhinolaringology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Azienda Ospedaliera Universitaria Policlinico ''Paolo Giaccone'', University of Palermo, Via del Vespro, 133, Palermo, 90127, Italy.
Angelo ImmordinoOtorhinolaringology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Azienda Ospedaliera Universitaria Policlinico ''Paolo Giaccone'', University of Palermo, Via del Vespro, 133, Palermo, 90127, Italy. angelo.immordino182@gmail.com.ORCID http://orcid.org/0000-0002-3414-6492
Salvatore GallinaOtorhinolaringology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Azienda Ospedaliera Universitaria Policlinico ''Paolo Giaccone'', University of Palermo, Via del Vespro, 133, Palermo, 90127, Italy.ORCID https://orcid.org/0000-0003-1137-7260
Antonino ManiaciYoung-Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS) Study Group, Paris, France.ORCID https://orcid.org/0000-0002-1251-0185
Jerome Rene LechienYoung-Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS) Study Group, Paris, France.
Christian Calvo-HenriquezYoung-Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS) Study Group, Paris, France.ORCID https://orcid.org/0000-0003-3580-0967
Alberto Maria SaibeneYoung-Otolaryngologists of the International Federation of Oto-Rhino-Laryngological Societies (YO-IFOS) Study Group, Paris, France.ORCID https://orcid.org/0000-0003-1457-6871
Federico SireciOtorhinolaringology Section, Department of Biomedicine, Neuroscience and Advanced Diagnostics, Azienda Ospedaliera Universitaria Policlinico ''Paolo Giaccone'', University of Palermo, Via del Vespro, 133, Palermo, 90127, Italy.ORCID https://orcid.org/0000-0002-9264-1184

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe control of epistaxis has always posed a significant challenge for otolaryngologists. One of the most viable options to address refractory cases is the ligation or cauterization of the sphenopalatine artery. The objective of this study was to assess the efficacy, safety, and long-term outcomes of these interventions. MATERIALS AND

methodsTwo independent otolaryngologists conducted a comprehensive search for studies dealing with management of uncontrolled/recurrent epistaxis by consulting the main scientific databases on the web, including PubMed, Google Scholar, Medline, EMBASE, Web of Science, and the Cochrane Library. The systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) statement. The criteria for considering studies for the review were based on the population, intervention, comparison, outcome, timing and setting (PICOTS) framework.

resultsSixteen studies were included in the systematic review, comprising a total of 454 patients. Among these, 289 individuals underwent ligation of the sphenopalatine artery, while 100 underwent cauterization of the same artery. Additionally, 56 patients underwent both ligation and cauterization of the sphenopalatine artery during the same surgery. The incidence of rebleeding and complications was respectively 12.1% (55/454) and 3% (14/454), resulting in relatively low rates in both cases.

conclusionsOur review emphasizes the increasing importance of surgical approaches, specifically ligation or cauterization of the sphenopalatine artery, in addressing refractory cases. The low incidence of complications, predominantly temporary decreased lacrimation in patients undergoing ligation of the sphenopalatine artery, highlights the safety and feasibility of these interventions.

Indexed as

CauteryEpistaxisRecurrenceArteriesHumansLigationEpistaxisReviewSphenopalatine artery cauterizationSphenopalatine artery ligation

Identifiers

PMID39069575
PMCPMC11564265

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.