Evidence map›Paper›PMID 39069572›Full record

Trial reportEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2024

Difference in the immediate effect on positional nystagmus for head positions with interval time during Epley maneuver: a randomized trial.

Takao Imai, Kayoko Higashi-Shingai, Yuya Ueno, Yumi Ohta, Takashi Sato, Takefumi Kamakura, Tomoko Iga, Shinji Mikami, Naomiki Kimura, Takashi Nakajima and 2 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Development of a new maneuver to rapidly restore positional nystagmus from benign paroxysmal positional vertigo fatigue in patients with posterior canal-type benign paroxysmal positional vertigo: a single-arm prospective interventional clinical trial.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Takao ImaiDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan. imaitakao@hotmail.com.ORCID http://orcid.org/0000-0002-1686-6787
Kayoko Higashi-ShingaiDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan.
Yuya UenoDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan.
Yumi OhtaDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan.
Takashi SatoDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan.
Takefumi KamakuraDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan.
Tomoko IgaDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan.
Shinji MikamiDepartment of Otorhinolaryngology - Head and Neck Surgery, Bell Land General Hospital, 500-3 Higashiyama, Naka-ku, Sakai-shi, Osaka, 599-8247, Japan.
Naomiki KimuraDepartment of Otorhinolaryngology - Head and Neck Surgery, Bell Land General Hospital, 500-3 Higashiyama, Naka-ku, Sakai-shi, Osaka, 599-8247, Japan.
Takashi NakajimaDepartment of Otorhinolaryngology - Head and Neck Surgery, Bell Land General Hospital, 500-3 Higashiyama, Naka-ku, Sakai-shi, Osaka, 599-8247, Japan.
Hiroto FujitaDepartment of Otorhinolaryngology - Head and Neck Surgery, Bell Land General Hospital, 500-3 Higashiyama, Naka-ku, Sakai-shi, Osaka, 599-8247, Japan.
Hidenori InoharaDepartment of Otorhinolaryngology - Head and Neck Surgery, Osaka, University Graduate School of Medicine, Osaka, Japan.

Funding

JSPS KAKENHI Grant 23K08941
6 · The paper itself

Abstract

objectivesThe Epley maneuver (EM) shows immediate effect, wherein disappearance of positional nystagmus occurs soon after the EM. Our previous study showed that setting interval times during the EM reduced the immediate effect. The purpose of this study is to identify the head position for which interval time reduces the immediate effect.

methodsFifty-one patients with posterior canal type of benign paroxysmal positional vertigo (BPPV) were randomly assigned to the following three groups: 10 min interval time set at the first head position of the EM in group A, at the third head position in group B, and at the fourth head position in group C. The primary outcome measure (POM) was the ratio of maximum slow-phase eye velocity of positional nystagmus soon after the EM, compared with that measured before the EM. A large ratio value indicates a poor immediate effect of the EM.

resultsThe POM in group A (0.07) was smallest (B: 0.36, C: 0.49) (p < 0.001). DISCUSSION: The interval times at the third and fourth head positions reduced the immediate effect of the EM. Our previous study showed that the effect of BPPV fatigue is continued by maintaining the first head position of the EM. BPPV fatigue constitutes fatigability of positional nystagmus with repeated performance of the Dix-Hallpike test. Our findings may be interpreted in accordance with the theory that the immediate effect of the EM is BPPV fatigue itself, because we observed that the effect of BPPV fatigue is strongest in group A.

Indexed as

Benign Paroxysmal Positional VertigoNystagmus, PhysiologicAdultAgedFemaleHeadHead MovementsHumansMaleMiddle AgedPatient PositioningPostureTime FactorsBPPV fatigueDix-hallpike testEpley maneuverMaximum slow-phase eye velocityPositional nystagmus

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.