Evidence map›Paper›PMID 39068636›Full record

ArticlePain and therapy2024

Transforaminal Steroid Injection After Dorsal Root Ganglion Pulsed Radiofrequency (DRG-PRF): Impact on Pain Intensity and Disability.

Matteo Luigi Giuseppe Leoni, Fabrizio Micheli, David Michael Abbott, Marco Cascella, Giustino Varrassi, Pasquale Sansone, Roberto Gazzeri, Monica Rocco, Marco Mercieri

Abstract read
In one paragraph

Article in Pain and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matteo Luigi Giuseppe LeoniDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy. matteolg.leoni@gmail.com.ORCID http://orcid.org/0000-0001-5228-3733
Fabrizio MicheliUnit of Interventional Pain Management, Guglielmo da Saliceto Hospital, Piacenza, Italy.
David Michael AbbottDepartment of Surgical, Pediatric and Diagnostic Sciences, University of Pavia, 27100, Pavia, PV, Italy.
Marco CascellaDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081, Baronissi, Italy.
Giustino VarrassiPaolo Procacci Foundation, 00193, Rome, Italy.
Pasquale SansoneDepartment of Woman, Child and General and Specialized Surgery, University of Campania "Luigi Vanvitelli", 81100, Naples, Italy.
Roberto GazzeriPain Therapy Unit, San Giovanni Addolorata Hospital, 00184, Rome, Italy.
Monica RoccoDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.
Marco MercieriDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDorsal root ganglion pulsed radiofrequency (DRG-PRF) is frequently used for the treatment of chronic lumbar radicular pain with good outcomes in terms of pain management. Transforaminal epidural steroid injection (TFESI) is often administered immediately after DRG-PRF to increase the anti-inflammatory effects, but support for the synergic mechanism is lacking in the literature. The aim of this study was to investigate the potential role of TFESI immediately after DRG-PRF and its possible role on pain intensity and patient disability.

methodsA database of patients who underwent DRG-PRF with or without TFESI immediately after DRG-PRF was retrospectively analysed; propensity score matching was applied to the analysis to reduce possible bias. Pain intensity (numerical rating scale [NRS]) and Oswestry disability index (ODI) were recorded pre-operatively and at the 1- and 3-month follow-up in the two groups of patients.

resultsA total of 252 patients were included in this retrospective analysis, 126 patients in the DRG-PRF + TFESI group and 126 patients in the DRG-PRF group after propensity score matching. Both groups displayed a significant reduction in pain intensity (NRS score reduction; p < 0.0001) and improvement in the ODI (p < 0.0001) from baseline at the 3-month follow-up. Interestingly, the use of TFESI after DRG-PRF was not associated with any clinical benefit as no difference in NRS and ODI was found between the two groups at the 1- and 3-month follow-ups.

conclusionsOur study revealed a significant pain reduction and disability improvement after DRG-PRF in patients with lumbar radicular pain. Interestingly, no positive role of TFESI immediately after DRG-PRF was observed. These findings suggest that DRG-PRF provides substantial pain relief, and no added benefit is obtained with subsequent steroid injection. Future prospective studies with expanded follow-up periods are needed to confirm these findings.

Indexed as

Dorsal root ganglionLow back painPulsed radiofrequencyRadicular painSteroid injectionTransforaminal

Identifiers

PMID39068636
PMCPMC11393363

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.