ArticleCardiovascular diabetology2024
Association between atherogenic index of plasma and all-cause mortality and specific-mortality: a nationwide population‑based cohort study.
Article in Cardiovascular diabetology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
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Who cites it
56 citing papers in PubMed.
- Association between the atherogenic index of plasma and prognosis in kidney transplant recipients: a retrospective cohort study.International urology and nephrology · 2026Article
- Tumor-driven arginine depletion induces T-cell metabolism reprogramming to suppress atherosclerosis in colorectal cancer.Acta pharmacologica Sinica · 2026Article
- Association between the atherogenic index of plasma trajectory and risk of cardiovascular diseases among hypertensive patients: a prospective cohort study.Cardiovascular diabetology. Endocrinology reports · 2026Article
- The association of nontraditional lipid parameters with all-cause and cardiovascular mortality: A national cohort study.Medicine · 2026Article
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- Atherogenic Index of Plasma Predicts the Onset and Progression of Cardio-Renal-Metabolic Multimorbidity: Evidence From a Nationwide Prospective Cohort Study.Journal of diabetes · 2026Article
- Lipid profile dynamics and associated cardiovascular disease risk indices in Chinese people living with human immunodeficiency virus receiving antiretroviral therapy.BMC infectious diseases · 2026Article
- Association of atherogenic index of plasma and cardiometabolic index with all-cause mortality and cardiovascular disease in NAFLD patients: NHANES 1999-2018.Cardiovascular diabetology · 2026Article
- Atherogenic index of plasma is associated with poor prognosis in diabetic patients with acute kidney injury.Frontiers in endocrinology · 2026Article
- Blood pressure-stratified associations of the atherogenic index of plasma with all-cause mortality: a 10-year rural cohort study in China.Frontiers in cardiovascular medicine · 2026Article
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- Association between circulating selenium levels and arterial stiffness: a nationwide cross-sectional study.International journal of surgery (London, England) · 2026Article
- Nonlinear and Age-Specific Associations Between Atherogenic Index of Plasma and Differential Cardiovascular Risk Profiles in US Adults.Cardiovascular therapeutics · 2026Article
- Atherogenic index of plasma and cardiovascular high-risk status in the ChinaHEART luohe cohort: multivariable association modeling with nonlinear dose-response and effect heterogeneity.Frontiers in endocrinology · 2026Article
- Association between combined atherogenic and frailty index and cardiovascular events: evidence from the CHARLS cohort.Cardiovascular diabetology · 2025Article
- Association between cumulative atherogenic index of plasma and dementia risk score in middle-aged and elderly adults: a longitudinal analysis of the CHARLS cohort.European journal of medical research · 2025Article
- Association of the atherogenic index of plasma with the risk of cardiovascular disease and death among diabetic or prediabetic adults.Endocrine · 2025Article
- Association of triglyceride-glucose index and atherogenic index of plasma with sarcopenia across different glucose metabolism states: the mediating role of oxidative stress and chronic inflammation.European journal of medical research · 2025Article
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14 authors.
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Abstract
backgroundAtherogenic index of plasma (AIP), a marker of atherosclerosis and cardiovascular disease (CVD). However, few studies have investigated association between AIP and all-cause mortality and specific-mortality in the general population.
methodsThis study included data from 14,063 American adults. The exposure variable was the AIP, which was defined as log10 (triglycerides/high-density lipoprotein cholesterol). The outcome variables included all-cause mortality and specific-mortality. Survey-weighted cox regressions were performed to evaluate the relation between AIP and all-cause mortality and specific-mortality. Weighted restricted cubic spline was conducted to examin the non-linear relationship.
resultsDuring 10 years of follow-up, we documented 2,077, 262, 854, and 476 cases of all-cause mortality, diabetes mortality, CVD mortality and cancer mortality, respectively. After adjustment for potential confounders, we found that atherogenic index of plasma (AIP) was significantly associated with an increased risk of diabetes mortality when comparing the highest to the lowest quantile of AIP in female (p for trend = 0.001) or participants older than 65 years (p for trend = 0.002). AIP was not significantly associated with all-cause mortality, CVD mortality and cancer mortality (p > 0.05). Moreover, a non-linear association was observed between AIP and all-cause mortality in a U-shape (p for non-linear = 0.0011), while a linear relationship was observed with diabetes mortality and non-diabetes mortality (p for linear < 0.0001).
conclusionsIn this study, there is a no significant association between high AIP levels and a high risk of all-cause and cardiovascular mortality. Besides, a higher AIP was significantly associated with an increased risk of diabetes mortality, which only found in women older than 65 years. AIP was associated with all-cause mortality in a U-shape. This association could be explained by the finding that higher AIP predicted a higher risk of death from diabetes, and that lower AIP predicted a higher risk of death from non-diabetes causes.
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